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Episode 53 continues where we left with the whole CRP measurement or no measurement discussion. James and Mike start with the Reynolds Risk Score and show how even at the extremes of CRP, absolute risks only change by around +/- 2% or so. Far more interesting is that there are now 2 studies showing clearly that good estimates of cardiovascular risk can be made without knowing lab values like cholesterol and CRP. All you have to basically do is look at the patient. Mike looks at James and declares that James is at very high risk of annoying Mike – so he does, just to show the evidence is solid.
Show Notes
1) Reynolds Risk Score
2) CRP goes up as weight goes up
3) Estimating cardiovascular risk estimates without knowing cholesterol or CRP
{ 6 comments… read them below or add one }
I sometimes wonder if “studies” (like JUPITER) are actually advertising media gimmicks…. but then I tell myself that such a thing could never happen.
And by the way… on this side of the pond…. and down south here… the expression is “pissing in the ocean”…. (and it has nothing to do with being drunk-unless you really ARE drunk and on one of our beaches where summer has been in full swing for quite a while!
Thanks for your great podcasts–great info and comedy.
Did you mean “CRP goes up as weight/BMI goes up” in 2 ?
Hi Jane – I had a re-listen to the podcast – when I first started talking about CRP and weight I think I did say as weight/BMI goes up so does CRP – or is there another place where I may have become confused or been confusing. Just let me know – and then I’ll just blame Mike
. The bottom line is, as you get heavier your CRP goes up. Thanks.
Hi Coolshade – I don’t think it is as simple as that – I think many of the people involved in these studies legitimately believe in the overall concept/question they are looking at, work hard to make it a “solid” study and so on – however, anything can, and often is marketed and I’m sure the funders of this study were not just being benevolent and saw a potential market if the results went their way. On your second point, we have the same expression but I was trying to keep the podcasts “G” rated. Thanks for listening to the podcasts.
Hi James,
I should have been clearer. It is the show notes that say ” 2) BMI goes up as weight goes up”
Jane – now I get it – made the change – thanks for listening and thanks for catching that slip-up!!
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