Episode 154: Using antibiotics - how to stop being damned if you do, damned if you don't

In episode 154, Mike and James discuss the whole issue of why we use antibiotics. We discuss patient preferences, the use of delayed antibiotics, diagnostic uncertainty and at the end of the podcast we realise that the whole thing is tricky and so we give tips and tricks for how to deal with all the confusion.

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Episode 153: Roflumilast when you add it on for COPD does it add up?

In episode 153, James and Mike attempt to breath life into a new agent for COPD called roflumilast. Unfortunately, by the end of the podcast we find out that the effect of this agent doesn't leave Mike and James breathless but unfortunately it will leave our COPD patients that way. 

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Episode 152: Leaking out the evidence around overactive bladders and urge incontinence

In episode 152, Mike and James stream to the listeners a synopsis of the literature associated with treatments for overactive bladder and urge incontinence. Despite constant interruptions by James, Mike is able to provide a torrent of useful tips and suggestions for this common problem.

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1) Diagnosing Incontinence

Ann Intern Med 2006;144:715-723 Read more »

Episode 151: PREMIUM Aiming high and long with two studies that should impact practice

In episode 151, James and Mike start of the new year with premium information so, by law we had to put it in a PREMIUM podcast. The first study we looked at was AIM-HIGH which showed us that we might need to re-assess how we use niacin and we finally have some reasonable data that helps us figure out how long to stay on a bisphosphonate.

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Episode 150: Respecting frailty in a cognitive way

In episode 150, the last for 2011, Mike and James elicit the help of Laurie Mallery and Paige Moorhouse from Halifax. Laurie and Paige guide us through a step-by step approach to deal with frailty and end of life care. We also discuss their PATH (Palliative and Therapeutic Harmonization) clinic developed for older people in Nova Scotia with chronic health conditions. Read more »

Episode 149: Definitively vague questions with vaguely definitive answers - PART III

In episode 149, Mike and James finally get to the last of the questions and discuss the use of vinegar for weight loss, surrogate markers and what to do about them, steroids for migraine, niacinamide for acne, statins for women, and what is the meaning of life. Read more »

Episode 148: Definitively vague questions with vaguely definitive answers - PART II

In episode 148, Mike and James return to the town of Questionville and attempt to answer riddles from near and far. Despite Mike having a cold, we tackle long acting insulins, exercise, multivitamins and varenecline with near Herculean-like abilities but provide answers that are much more on the mere-mortal side.

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1) Long acting insulins Read more »

Episode 147: Definitively vague questions with vaguely definitive answers

In episode 147, Mike and James cover the issue of humor in teaching, put drugectomies in LTC facilities into perspective, discuss the use of antibiotics in COPD, and finally contextualize bisphophonates and estrogen for fracture reduction. At the end they agree that the 30 minutes of podcast excellence should leave the audience laughing and crying but not for the right reasons. Read more »