In episode 58, the fourth in our installment of podcasts on diabetes, we briefly talk about the evidence surrounding intensive glucose lowering (ACCORD, ADVANCE, VADT and UKPDS trials) – podcasts #9 and #38 did this in more detail. At the end of the podcast, Mike identifies many of James’ flaws, but does it with compassion and kindness; at least he says he does.
1) Does tight glycemic control burden patients with complex treatment programs, hypoglycemia, weight gain, and costs and offers uncertain benefits in return?
2) ACCORD and ADVANCE studies
3) VADT trial N Engl J Med 2009;360:129-39
Also listen to Episode 38: New trials you need to know about
4) Glucose lowering meta-analysis – do the results support the conclusions?
5) UKPDS data
6)UKPDS – 10 year update (recent results)