TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 82: Lost faith in surrogates yet? ACCORD challenges beliefs again

In episode 82, James and Mike discuss the latest results from the ACCORD trial. While the results really showed no difference between the groups, these results should make a difference in what you do. During much of the podcast, Mike does an unbelievable impersonation of a parrot but, we aren’t sure if anyone will notice that difference.

Show notes

1) ACCORD – glucose lowering

NEJM 208;358:2545-9

2) ACCORD – blood pressure lowering

NEJM 2010:10.1056/NEJMoa1001286

3) ACCORD – cholesterol lowering with fenofibrate

NEJM 2010:10.1056/NEJMoa1001282

3) FIELD – fenofibrate

Lancet 2005;366:1849-61

3) Studies, systematic reviews and meta-analyses of fibrates

Am Heart J 2007;154:943-53

Am J Med 2009; 122: 962.e1-962.e8

J Am Coll Cardiol 2005;45:185–97

Arch Intern Med. 2005;165:725-730

Int J Cardiol 2009; doi:10.1016/j.ijcard.2008.11.211

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