Generic Brand Name UBC formulary Drug Category AGS Beers Criteria for Potentially Inappropriate Medication Use in Older Adults (2012) JUST TABLE 2 STOPP 1306 Feb 2013 version ANTICHOLINERGIC RANKINGPolypharmacy Guidance for Prescribing in Frail Adults (Wales) RX files Anticholinergic "Top reasons for hospitalization BMJ 2004; 329; 15-17,Br J Clin Pharmacol 2006; 63:2; 136-147" Emergency Hospitalizations for Adverse Drug Events in Older Americans NEJM 2011;365:21:2002-2012 HEDIS from Supplementary material in NEJM 2011;365:21:2002-2021 dutasteride Avodart 5-alpha reductase inhibitors None None finasteride Proscar 5-alpha reductase inhibitors None None benazepril Lotensin ACE inhibitors None None x x captopril Capoten ACE inhibitors None None x x cilazapril Inhibace ACE inhibitors None None x x enalapril Vasotec ACE inhibitors None None x x fosinopril Monopril ACE inhibitors None None x x lisinopril "Prinivil, Zestril" ACE inhibitors None None x x perindopril Aceon ACE inhibitors None None x x quinapril Accupril ACE inhibitors None None x x ramipril Altace x ACE inhibitors None None x x trandolapril Mavik ACE inhibitors None None x x acetaminophen Tylenol x Acetaminophen None None atomoxetine Strattera ADHD None None dextroamphetamine "Adderal, Adderal XR, Dexedrine" ADHD None None lisdexamphetamine Vyvanse ADHD None None methylphenidate Ritalin x ADHD None None x mixed salts amphetamine ADHD None None eplerenone Inspra Aldosterone antagonists None None spironolactone Aldactone x Aldosterone antagonists Avoid in patients with heart failure or with a CrCI < 30 mL/min if dose >25mg/d None alfuzosin Uroxatral Alpha-blockers None Avoid in males with frequent incontinence or long term urinary catheter x doxazosin Cardura Alpha-blockers Avoid as antihypertensive Avoid in males with frequent incontinence or long term urinary catheter x tamsulosin Flomax x Alpha-blockers None Avoid in males with frequent incontinence or long term urinary catheter x terazosin Hytrin x Alpha-blockers Avoid as antihypertensive Avoid in males with frequent incontinence or long term urinary catheter x azilsartan Edarbi Angiotensin 2 blockers None None x x candesartan Atacand Angiotensin 2 blockers None None x x eprosartan Teveten Angiotensin 2 blockers None None x x irbesartan Avapro Angiotensin 2 blockers None None x x losartan Cozaar x Angiotensin 2 blockers None None x x olmesartan Benicar Angiotensin 2 blockers None None x x telmisartan Micardis Angiotensin 2 blockers None None x x valsartan Diovan Angiotensin 2 blockers None None x x amiodarone Cordarone x Antiarrhythmic Avoid antiarrhythmic drugs as first-line treatment of atrial fibrillation None disopyramide Norpace Antiarrhythmic Avoid None y dofetilide Tikosyn Antiarrhythmic Avoid antiarrhythmic drugs as first-line treatment of atrial fibrillation None dronedarone Multaq Antiarrhythmic Avoid antiarrhythmic drugs as first-line treatment of atrial fibrillation None flecainide Tambocor Antiarrhythmic Avoid antiarrhythmic drugs as first-line treatment of atrial fibrillation None mexiletine Mexitil Antiarrhythmic None None procainamide Pronestyl Antiarrhythmic Avoid antiarrhythmic drugs as first-line treatment of atrial fibrillation None propafenone Rythmol Antiarrhythmic Avoid antiarrhythmic drugs as first-line treatment of atrial fibrillation None quinidine Antiarrhythmic Avoid antiarrhythmic drugs as first-line treatment of atrial fibrillation None ipratropium Atrovent Anticholinergics None Avoid nebulized form if glaucoma tiotropium Spiriva x Anticholinergics None None azatadine Zadine Antihistamine None None brompheniramine Dimetane Antihistamine Avoid Avoid y cetirizine Zyrtec Antihistamine None None 2 points chlorpheniramine Chlortripolon Antihistamine Avoid Avoid 3 points y x clemastine Tavist Antihistamine Avoid Avoid cyproheptadine Periactin Antihistamine Avoid Avoid y x desloratadine Clarinex Antihistamine None None dimenhydrinate Dramamine x Antihistamine None None y diphenhydramine Benadryl Antihistamine Avoid Avoid y x fexofenadine Allegra Antihistamine None None hydroxyzine Atarax x Antihistamine Avoid Avoid 3 points y x ketotifen Zaditor Antihistamine None None loratadine Claritin Antihistamine None None 2 points promethazine Phenadoz Antihistamine Avoid Avoid y x trimeprazine Vallergan Antihistamine None None triprolidine Histex Antihistamine Avoid Avoid alprazolam Xanax Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x chlordiazepoxide Librium Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x x clobazam Onfi Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x clonazepam Klonopin Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x diazepam Valium Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x x flurazepam Dalmane Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x x lorazepam Ativan x Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x midazolam Versed Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x oxazepam Serax Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x temazepam Restoril Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x triazolam Halcion Benzodiazepines "Avoid benzodiazepines for treatment of insomnia, agitation, or delirium " "Avoid long term (>1month) use, if fallen in last 3 months" x formoterol Oxese Beta-agonists None None salbutamol/albuterol Ventolin x Beta-agonists None None salmeterol Serevent Beta-agonists None None acebutolol Sectral Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x atenolol Tenormin Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x bisoprolol Zebeta Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x carvedilol Coreg x Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x labetalol Trandate Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x metoprolol "Toprol XL, Lopressor" x Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x nadolol Corgard Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x nebivolol Bystolic Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x oxprenolol Trasacor Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x pindolol Visken Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x propranolol Inderal x Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x sotalol "Sorin, Betapace" x Beta-blockers Avoid antiarrhythmic drugs as first-line treatment of atrial fibrillation Avoid in those with diabetes mellitus and frequent hypoglycemic events x timolol Blocadren Beta-blockers None Avoid in those with diabetes mellitus and frequent hypoglycemic events x abatacept Orencia Biologics None None adalimumab Humira Biologics None None certolizumab Cimzia Biologics None None denosumab Xgeva Biologics None None efalizumab Raptiva Biologics None None etanercept Enbrel Biologics None None infliximab Remicade Biologics None None omalizumab Xolair Biologics None None rituximab Rituxan Biologics None None tocilizumab Actemra Biologics None None ustekinumab Stelara Biologics None None alendronate Fosamax x Bisphosphonates None None clodronate Clasteon Bisphosphonates None None etidronate Didronel Bisphosphonates None None pamidronate Aredia Bisphosphonates None None risedronate Actonel Bisphosphonates None None amlodipine Norvasc x Calcium antagonists None None x diltiazem "Cardizem, Cartia XT, Tazia XT" Calcium antagonists other None "Avoid in heart failure, chronic constipation, or with other vasodilator drugs" x felodipine Plendil Calcium antagonists pines None Avoid in chronic constipation or with other vasodilator drugs x nifedipine "Adalat, Procardia" Calcium antagonists pines Avoid if immediate release Avoid in chronic constipation or with other vasodilator drugs x x short acting only verapamil "Verelan, Calan, Isoptin" Calcium antagonists other None "Avoid in combination with beta-blocker, other vasodilators, or heart failure" x cholestyramine Questran Cholesterol other None None colestipol Colestid Cholesterol other None None ezetimibe Zetia Cholesterol other None None donepezil Aricept x Cholinesterase inhibitors None None colchicine Colcrys x Colchicine None None bisacodyl Dulcolax Constipation None None castor oil Constipation None None docusate Colace Colace None None glycerin Constipation None None lactulose Constipation None None magnesium hydroxide Milk of Magnesia Constipation None None magnesium sulfate Epsom salts Constipation None None methylnaltrexone Relistor Constipation None None mineral oil "Fleet Enema Mineral Oil, Lansoyl" Constipation Avoid None polycarbophil Prodiem Constipation None None polyethylene glycol "Lax-A-Day, Pegalax, Restoralax" Constipation None None psyllium Metamucil Constipation None None senna Senokot x Constipation None None sodium phosphates Fleet Enema Constipation None None dexamethasone Decadron Corticosteroids None Avoid for COPD if inhaled corticosteroids could be used x hydrocortisone x Corticosteroids None Avoid for COPD if inhaled corticosteroids could be used x methylprednisolone Medrol Corticosteroids None Avoid for COPD if inhaled corticosteroids could be used x prednisone "Sterapred, Orasone, Deltasone" x Corticosteroids None Avoid for COPD if inhaled corticosteroids could be used x bupropion "Wellbutrin, Zyban, Budeprion" x Depression other None None x maprotiline Ludiomil Depression other None None x mirtazapine Remeron x Depression other None None 1 point x moclobemide Manerix Depression other None None x phenelzine Nardil Depression other None None x tranylcypromine Parnate Depression other None None x acarbose Precose Diabetes other None None x linagliptan "Tradjenta, Trajenta" Diabetes other None None x liraglutide Victoza Diabetes other None None x nateglinide Starlix Diabetes other None None x repaglinide Prandin Diabetes other None None x sitagliptin Januvia x Diabetes other None None x diphenoxylate Lomotil Diarrhea None Avoid for treatment of diarrhea of unknown cause or severe infective gastroenteritis y x loperamide Imodium x Diarrhea None Avoid for treatment of diarrhea of unknown cause or severe infective gastroenteritis 2 points y digoxin "Lanoxin, Digitek" x Digoxin Avoid if >0.125mg/d Avoid at a long-term dose > 125?g/day with impaired renal function x x furosemide Lasix x Diuretics None "Avoid for ankle edema, hypertension" x metolazone Zaroxolyn Diuretics None "Avoid for ankle edema, hypertension" x torsemide Demadex Diuretics None "Avoid for ankle edema, hypertension" x carbamazepine Tegretol x Epilepsy None None y divalproex Depakote Epilepsy None None gabapentin Neurontin x Epilepsy None None lamotrigine Lamictal x Epilepsy None None levetiracetam Keppra x Epilepsy None None oxcarbazepine Trileptal Epilepsy None None y phenytoin Dilantin x Epilepsy None None pregabalin Lyrica CHECK WHY NOT PAIN Epilepsy None None topiramate Topamax x Epilepsy None None valproic acid Depakene x Epilepsy None None vigabatrin Sabril Epilepsy None None sildenafil Viagra Erectile None None tadalafil Cialis Erectile None None vardenafil Levitra Erectile None None yohimbine Erectile None None estrogens x Estrogen/progesterone Avoid oral and topical patch "Avoid with history of breast cancer or venous thromboembolism, or without progestogen in patients with intact uterus" x levonorgestrel Estrogen/progesterone None None norethindrone Estrogen/progesterone None None progesterone x Estrogen/progesterone None None bezafibrate Bezalip Fibrates None None fenofibrate Tricor Fibrates None None gemfibrozil Lopid Fibrates None None chlorpromazine Thorazine First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" 3 points y flupenthixol Fluanxol First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" fluphenazine Prolixin First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" y haloperidol Haldol x First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" 1 point loxapine Loxapac First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" y methotrimeprazine Nosinan First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" y perphenazine Trilafon First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" y pimozide Orap First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" y prochlorperazine Compazine First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" 2 points y thiothixene Navane First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" y trifluoperazine Stelazine First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" y zuclopenthixol Clopixol First generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" antacids: Al++/Mg++ Gastrointestinal other None None bismuth subsalicylate Pepto-Bismol Gastrointestinal other None None domperidone Motilium Gastrointestinal other None None metoclopramide Reglan x Gastrointestinal other "Avoid, unless for gastroparesis" Avoid with Parkinsonism pioglitazone Actos Glitazones None None x rosiglitazone Avandia x Glitazones None None x probenecid Benemid Gout other None None sulfinpyrazone Anturan Gout other None None cimetidine Tagamet H2 antagonists None None 2 points y famotidine Pepcid H2 antagonists None None nizatidine Axid H2 antagonists None None ranitidine Zantac x H2 antagonists None None 1 point y enoxaparin Lovenox x Heparin None None tinzaparin Innohep Heparin None None aliskiren Tekturna Hypertension other None None amiloride Midamor x Hypertension other None None clonidine Catapres Hypertension other Avoid as a first-line antihypertensive None hydralazine "Apresoline, Dralzine" Hypertension other None None methyldopa Aldomet Hypertension other Avoid None prazosin Minipress Hypertension other Avoid as antihypertensive None 5-aminosalicylic acid "Pentasa, Rowasa, Asacol" x IBD None None olsalazine Dipentum IBD None None darifenacin Enablex Incontinence None None fesoterodine Toviaz Incontinence None None flavoxate Urispas Incontinence None None mirabegron Myrbetriq Incontinence None None oxybutynin Ditropan Incontinence None None 3 points solifenacin Vesicare Incontinence None None tolterodine Detrol x Incontinence None None beclomethasone Beclovent Inhaled steroids None None budesonide Pulmicort Inhaled steroids None None ciclesonide Alvesco Inhaled steroids None None fluticasone Flovent x Inhaled steroids None None insulin x Insulin Avoid if sliding scale None x montelukast Singulair x Leukotriene antagonists None None zafirlukast Accolate Leukotriene antagonists None None metformin Glucophage x Metformin None None dihydroergotamine DHE 45 Migraine other None None ergotamine Ergomar Migraine other None None flunarizine Sibelium Migraine other None None methysergide Sansert Migraine other None None pizotifen Sandomigran Migraine other None None misoprostol Cytotec Misoprostol None None buprenorphine Buprenex Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x codeine Narcotics None Avoid for treatment of diarrhea of unknown cause or severe infective gastroenteritis x x fentanyl Duragesic x Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x hydrocodone Vicodin Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x hydromorphone Dilaudid Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x meperidine Demerol Narcotics Avoid "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" y x x x methadone x Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x morphine x Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x oxycodone Oxycontin Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x pentazocine Talwin Narcotics Avoid "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x x propoxyphene Darvon Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x x tramadol Ultram x Narcotics None "Avoid as first-line therapy for mild to moderate pain, for more than 2 weeks in those with chronic constipation, long-term use in dementia unless for chronic pain, those with recurrent falls" x x dolasetron Anzemet Nausea None None ondansetron Zofran Nausea None None scopolamine Nausea None None x niacin Niaspan Niacin None None isosorbide dinitrate or 5-mononitrate "Imdur, ISMO" Nitrates None None nitroglycerin NitroStat x Nitrates None None dabigatran Pradaxa x NOAC None None x rivaroxaban Xarelto NOAC None None x ticagrelor Brilinta NOAC None None x chloral hydrate Noctec Non-benzodiazepine sedatives Avoid None x eszopiclone Lunesta Non-benzodiazepine sedatives Avoid chronic use greater than 90 days None x zaleplon Sonata Non-benzodiazepine sedatives Avoid chronic use greater than 90 days None x zolpidem Ambien Non-benzodiazepine sedatives Avoid chronic use greater than 90 days None x zopiclone Imovane x Non-benzodiazepine sedatives Avoid chronic use greater than 90 days None x ASA Aspirin x NSAIDs None "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x x celecoxib Celebrex x NSAIDs None "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x diclofenac "Cataflam, Voltaren" NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x diflunisal Dolobid NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x etodolac Lodine NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x flurbiprofen Ansaid NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x ibuprofen "Motrin, Advil" x NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x indomethacin Indocid NSAIDs Avoid "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x ketoprofen Orudis NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x ketorolac Toradol NSAIDs Avoid "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x x lumiracoxib Prexige NSAIDs None "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x mefenamic acid Ponstel NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x meloxicam Mobic NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x nabumetone Relafen NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x naproxen "Aleve , Naprosyn , Anaprox" NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x oxaprozin Daypro NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x phenylbutazone NSAIDs None "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x piroxicam Feldene NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x sulindac Clinoril NSAIDs Avoid chronic use unless other alternatives are not effective and patient can take gastroprotective agent (proton pump inhibitor or misoprostol) "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x tenoxicam Mobiflex NSAIDs None "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x tiaprofenic acid Surgam NSAIDs None "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x tolmetin Tolectin NSAIDs None "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x zoledronic acid Aclasta NSAIDs None "Avoid with history of peptic ulcer disease or GI bleeding unless with concurrent H2RA, PPI, or misoprostil, with moderate-severe hypertension, with heart failure, with warfarin, with chronic renal failure, for long term (>3 months) for osteoarthritis unless simple analgesics are not effective, for chronic treatment of gout where there is no contraindication to allopurinol, with long term (>3 months) corticosteroids " x calcitonin Calcimar Osteoporosis other None None calcitriol Rocaltrol Osteoporosis other None None teriparatide Forteo Osteoporosis other None None amantadine Symmetrel Parkinson's None None y levodopa x Parkinson's None None pramipexole Mirapex x Parkinson's None None procyclidine Kemadrin Parkinson's None None y rasagiline Azilect Parkinson's None None ropinirole Requip Parkinson's None None selegiline Zelapar Parkinson's None None tolcapone Tasmar Parkinson's None None trihexyphenidyl Artane Parkinson's Avoid None y dexlansoprazole Dexilant PPIs None Avoid for peptic ulcer disease at full therapeutic dosage for >8 weeks esomeprazole Nexium PPIs None Avoid for peptic ulcer disease at full therapeutic dosage for >8 weeks lansoprazole Prevacid PPIs None Avoid for peptic ulcer disease at full therapeutic dosage for >8 weeks omeprazole Prilosec x PPIs None Avoid for peptic ulcer disease at full therapeutic dosage for >8 weeks pantoprazole Protonix PPIs None Avoid for peptic ulcer disease at full therapeutic dosage for >8 weeks rabeprazole Aciphex PPIs None Avoid for peptic ulcer disease at full therapeutic dosage for >8 weeks raloxifene Evista Raloxifene None None aripiprazole Abilify x Second generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" asenapine Saphris Second generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" clozapine Clozaril Second generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" 2 points y lurasidone Latuda Second generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" olanzapine Zyprexa x Second generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" y quetiapine Seroquel Second generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" 1 point y risperidone Risperdal Second generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" ziprasidone Geodon Second generation antipsychotics None "Avoid for long-term (>1 month) as hypnotics, with Parkinsonism, if fallen in past 3 months" nicotine x Smoking cessation None None varenicline Chantix Smoking cessation None None desvenlafaxine "Khedezla, Pristiq" SNRI None None x venlafaxine Effexor SNRI None None x citalopram Celexa x SSRI None Avoid with a history of clinically significant hyponatremia x escitalopram Lexapro SSRI None Avoid with a history of clinically significant hyponatremia x fluoxetine Prozac SSRI None Avoid with a history of clinically significant hyponatremia x fluvoxamine Luvox SSRI None Avoid with a history of clinically significant hyponatremia x paroxetine Paxil SSRI None Avoid with a history of clinically significant hyponatremia 1 point y x sertraline Zoloft SSRI None Avoid with a history of clinically significant hyponatremia x atorvastatin Lipitor x Statins None None fluvastatin Lescol Statins None None lovastatin Mevacor Statins None None pravastatin Pravachol Statins None None rosuvastatin Crestor Statins None None simvastatin Zocor Statins None None sucralfate Carafate Sucralfate None None chlorpropamide Diabinese Sulfonylureas Avoid Avoid for type 2 diabetes x x gliclazide Diamicron Sulfonylureas None None x glimepiride Amaryl Sulfonylureas None None x glyburide "DiaBeta, Glynase, Micronase" x Sulfonylureas Avoid Avoid for type 2 diabetes x tolbutamide Orinase Sulfonylureas None None x amitriptyline Elavil x TCA Avoid "Avoid with dementia, glaucoma, cardiac conductive abnormalities, constipation, opioids, calcium channel blockers, prostatism or prior history of urinary retention" 3 points y x x clomipramine Anafranil TCA Avoid "Avoid with dementia, glaucoma, cardiac conductive abnormalities, constipation, opioids, calcium channel blockers, prostatism or prior history of urinary retention" y x desipramine Norpramin TCA None "Avoid with dementia, glaucoma, cardiac conductive abnormalities, constipation, opioids, calcium channel blockers, prostatism or prior history of urinary retention" y x doxepin "Sinequan, Prudoxin, Zonalon, Silenor" TCA Avoid if >6mg/day "Avoid with dementia, glaucoma, cardiac conductive abnormalities, constipation, opioids, calcium channel blockers, prostatism or prior history of urinary retention" y x imipramine Tofranil TCA Avoid "Avoid with dementia, glaucoma, cardiac conductive abnormalities, constipation, opioids, calcium channel blockers, prostatism or prior history of urinary retention" 3 points y x nortriptyline "Pamelor, Aventyl" TCA None "Avoid with dementia, glaucoma, cardiac conductive abnormalities, constipation, opioids, calcium channel blockers, prostatism or prior history of urinary retention" 2 points y x trazodone Desyrel TCA None "Avoid with dementia, glaucoma, cardiac conductive abnormalities, constipation, opioids, calcium channel blockers, prostatism or prior history of urinary retention" 1 point x trimipramine Surmontil TCA Avoid "Avoid with dementia, glaucoma, cardiac conductive abnormalities, constipation, opioids, calcium channel blockers, prostatism or prior history of urinary retention" x testosterone Androgel x Testosterone Avoid None bumetanide Bumex Thiazides None Avoid with history of gout chlorthalidone "Thalitone, Hygroton" Thiazides None Avoid with history of gout hydrochlorothiazide Microzide Thiazides None Avoid with history of gout indapamide Lozol Thiazides None Avoid with history of gout triamtereneHCTZ?? "Dyazide, Maxzide" Thiazides None Avoid with history of gout levothyroxine "Synthroid, Levoxyl , Levothroid" x Thyroid None None almotriptan Axert Triptans None None eletriptan Relpak Triptans None None frovatriptan Frova Triptans None None naratriptan Amerge Triptans None None rizatriptan Maxalt Triptans None None sumatriptan Imitrex x Triptans None None zolmitriptan Zomig Triptans None None calcium x Vitamins/supplements None None folic acid Vitamins/supplements None None L-tryptophan Vitamins/supplements None None omega 3s Vitamins/supplements None None thiamine Vitamins/supplements None None vitamin C Vitamins/supplements None None vitamin E Vitamins/supplements None None warfarin Coumadin x Warfarin None None x x orlistat Xenical Weight loss None None allopurinol Zyloprim x Xanthine oxidase inhibitors None None acetazolamide Diamox None None acitretin Soriatane None None alefacept Amevive None None alfacalcidol None None anakinra Kineret None None auranofin Ridaura None None azathioprine Imuran x None None baclofen Lioresal x None None 2 points y benztropine Cogentin Avoid None y bromocriptine Parlodel None None budesonide/formoterol Symbicort None None buserelin Suprefact None None buspirone BuSpar None None butalbital Butisol None None chloroquine Aralen None None cinacalcet Sensipar None None clomiphene Clomid x None None clopidogrel Plavix x None None x x cyclobenzaprine Flexeril Avoid None y x cyclosporine Restasis x None None danazol Danocrine None None dantrolene Dantrium None None darbepoetin alfa Aranesp None None dextromethorphan Robitussin None None dicyclomine Bentyl Avoid None y x dipyridamole Persantine Avoid None x x short acting only dronabinol Marinol None None fluticasone/salmeterol Advair x None None glucosamine None None hydroxychloroquine Plaquenil None None interferon alfa Intron A None None iron None None isoniazid None None isotretinoin Accutane x None None leuprolide Lupron None None lidocaine "Lidoderm (Patch), Xylocaine (Injection)" None None liothyronine Cytomel None None lithium Lithobid x None None y memantine Namenda x None None mercaptopurine Purinethol None None methazolamide None None methimazole x None None methocarbamol Robaxin Avoid None y x methotrexate Rheumatrex x None None methoxsalen Oxsoralen None None metronidazole Flagyl None None midodrine Proamatine None None nafarelin Synarel None None octreotide Sandostatin None None orphenadrine Norflex Avoid None y x peginterferon alfa "Pegasys, Pegintron " None None penicillamine "Depen, Cuprimine" None None pentoxifylline Trental None None phenobarbital Donnatal x Avoid None x x prasugrel Effient None None x primaquine None None primidone Mysoline None None propylthiouracil None None prucalopride Resotran None None pseudoephedrine None None quinine None None sulfasalazine Azulfidine None None tacrolimus Prograf None None theophylline TheoDur None Avoid as monotherapy for COPD ticlopidine Ticlid Avoid None x tizanidine Zanaflex None None y trimetrexate Neutrexin None None vitamin D x None None carisoprodol Soma x glipizide Glucotrol guaifenesin Robitussin ibandronate Boniva meclizine Anti-vert potassium chloride "Slow-K, Klor-con" thioridazine x