May improve symptoms?	May reduce fuuture illness OUTCOMES) 	EFFECT SIZE	May cause harm?	Total Score	NEW TAPER	Taper	Reduce dose	Frequency	What to Watch for	Monitor	Other issues to consider drug interactions		Taper	Taper	Approach 	Monitor				
Class	Drug Category	Indication	yes(0)/maybe(1)/no (2)	yes(0)/somewhat(1)/no(2)		minimal or none (0)/some (1)/lots(2)	0-6		y/n	%	every X weeks		Signs and symptoms			Evid Based Med August 2013	A practical guide to stopping medicines in older people	A practical guide to stopping medicines in older people	A practical guide to stopping medicines in older people				
	Acetaminophen	osteoarthritis	1	2		0		Tapering not required	No														
	Acetaminophen	rheumatoid arthritis	2	2		0		Tapering not required	No														
	Acetaminophen	unknown	2	2		0		Tapering not required															
	Acetaminophen	other 	??	??		0		Tapering not required															
	Anticholinergics	asthma	0	1		0		Tapering not required															
	Anticholinergics	chronic obstructive lung disease	0	1		0		Tapering not required															
	Anticholinergics	unknown	2	2		0		Tapering not required															
	Anticholinergics	other 	??	??		0		Tapering not required															
	ASA	afib/valve	2	0		0		Tapering not required	No														
	ASA	previous heart attack or stroke	2	0		0		Tapering not required	No														
	Beta-agonists	chronic obstructive lung disease	0	1		0		Tapering not required	No														
Respiratory agents	Beta-agonists	asthma	0	2		0		Tapering not required	No				"shortness of breath, limitation of activity"										
	Beta-agonists	unknown	2	2		0		Tapering not required															
	Beta-agonists	other 	??	??		0		Tapering not required															
Anti-resorption	Bisphosphonates	osteoporosis/previous fracture	1	0		0		Tapering not required	No														
	Bisphosphonates	unknown	2	2		0		Tapering not required															
	Bisphosphonates	other 	??	??		0		Tapering not required															
	"Cholesterol other (ezetimibe, cholestyramine, colestipol)"	unknown	2	2		0		Tapering not required															
	"Cholesterol other (ezetimibe, cholestyramine, colestipol)"	other 	??	??		0		Tapering not required															
	Colace	constipation	2	2		0		Tapering not required															
Anticonstipation	Constipation	constipation	0	2		0		"If used daily for more than 3-4 weeks. Reduce the dose by 25% every 3 to 4 days. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	reduce by 50% every 1-2 weeks to acceptable bowel movement routine		constipation											
	Constipation	unknown	2	2		0		"If used daily for more than 3-4 weeks. Reduce the dose by 25% every 3 to 4 days. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				constipation											
	Constipation	other 	??	??		0		"If used daily for more than 3-4 weeks. Reduce the dose by 25% every 3 to 4 days. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				constipation											
Antidiarrhea	Diarrhea	diarrhea	0	2		0			Yes	reduce by 50% every 1-2 weeks to acceptable bowel movement routine													
Erectile dysfunction	Erectile dysfunction	erectile dysfunction	0	2		0		Tapering not required	No														
	Erectile dysfunction	unknown	2	2		0		Tapering not required															
	Erectile dysfunction	other 	??	??		0		Tapering not required															
Hormones	Estrogen/progesterone	menopausal symptoms (hot flashes etc)	0	2		0		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"hot flashes, weight gain, insomnia, anxiety"											
	Estrogen/progesterone	unknown	2	2		0		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"hot flashes, weight gain, insomnia, anxiety"											
	Estrogen/progesterone	other 	??	??		0		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"hot flashes, weight gain, insomnia, anxiety"											
	Fibrates	unknown	2	2		0		Tapering not required															
	Fibrates	other 	??	??		0		Tapering not required															
	Fibrates	no history of heart attack or stroke	2	0		0		Tapering not required	No														
Gastrointestinal other	"Gastrointestinal other (antacids, domperidone, metoclopramide)"	heartburn/GERD	0	2		0			Yes	reduce by 50% every 1-2 weeks to symptoms													
	"Gastrointestinal other (antacids, domperidone, metoclopramide)"	unknown	2	2		0																	
	"Gastrointestinal other (antacids, domperidone, metoclopramide)"	other 	??	??		0																	
Anti-ulcerants	H2 antagonists	heartburn/GERD	0	2		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	H2 antagonists	ulcer prevention	2	2		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	H2 antagonists	unknown	2	2		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	H2 antagonists	other 	??	??		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	Inhaled steroids	asthma	0	1		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	50%	every week	"shortness of breath, limitation of activity, need for rescue puffer"	"cough at night SOB, limitation activity "										
	Inhaled steroids	chronic obstructive lung disease	2	1		0		Tapering not required	No														
	Inhaled steroids	unknown	2	2		0																	
	Inhaled steroids	other 	??	??		0																	
	Leukotriene antagonists	asthma	1	1		0		Tapering not required	No														
	Leukotriene antagonists	chronic obstructive lung disease	2	2		0		Tapering not required	No														
	Leukotriene antagonists	unknown	2	2		0		Tapering not required															
	Leukotriene antagonists	other 	??	??		0		Tapering not required															
	Metformin	type 2 diabetes with high glucose symptoms	0	0		0		Tapering not required				"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
Antidiabetes	Metformin	type 2 diabetes	2	0		0		Tapering not required	No			"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	Metformin	unknown	2	2		0		Tapering not required															
	Metformin	other 	??	??		0		Tapering not required															
	PPIs	heartburn/GERD	0	2		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	PPIs	ulcer prevention	2	2		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	PPIs	unknown	2	2		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	PPIs	other 	??	??		0		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
Lipid regulators	Statins	no history of heart attack or stroke	2	0		0		Tapering not required	No														
	Statins	previous heart attack or stroke	2	0		0		Tapering not required	n (?studyMIKE)														
	Statins	unknown	2	2		0		Tapering not required															
	Statins	other 	??	??		0		Tapering not required															
	Sucralfate	ulcer prevention	2	2		0		Tapering not required															
	Sucralfate	unknown	2	2		0		Tapering not required															
	Sucralfate	other 	??	??		0		Tapering not required															
Thyroid	Thyroid	hypothyroid symptoms	0	2		0		Tapering not required	don't stop			"return of hypothyroid symptoms (tiredness, weakness, weight gain, hair loss, constipation, depression, coarse dry hair, hair loss)"											
	Thyroid	prevention but no symptoms HIGH TSH NUMBER	2	2		0		Tapering not required				"return of hypothyroid symptoms (tiredness, weakness, weight gain, hair loss, constipation, depression, coarse dry hair, hair loss)"											
	Thyroid	unknown	2	2		0		Tapering not required				"return of hypothyroid symptoms (tiredness, weakness, weight gain, hair loss, constipation, depression, coarse dry hair, hair loss)"											
	Thyroid	other 	??	??		0		Tapering not required				"return of hypothyroid symptoms (tiredness, weakness, weight gain, hair loss, constipation, depression, coarse dry hair, hair loss)"											
Antimigraine	Triptans	migraine	0	2		0		Tapering not required	No														
	Triptans	unknown	2	2		0		Tapering not required															
	Triptans	other 	??	??		0		Tapering not required															
		unknown	2	2		0		Tapering not required															
		other 	??	??		0		Tapering not required															
	5-alpha reductase inhibitors	benign prostatic hyperplasia	1	1		1		Tapering not required															
	5-alpha reductase inhibitors	unknown	2	2		1		Tapering not required															
	5-alpha reductase inhibitors	other 	??	??		1		Tapering not required															
ACE inhibitors	ACE inhibitors	blood pressure	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	ACE inhibitors	heart failure	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	ACE inhibitors	previous heart attack or stroke	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	ACE inhibitors	kidney disease	2	1		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	ACE inhibitors	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	ACE inhibitors	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
ADHD	ADHD	ADHD	0	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	taper like BP pills													
	ADHD	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	ADHD	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	Aldosterone antagonists	heart failure	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	other bp drugs		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Aldosterone antagonists	blood pressure	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	other bp drugs		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Aldosterone antagonists	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Aldosterone antagonists	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
Urinary tract	Alpha-blockers	benign prostatic hyperplasia	1	1		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	Alpha-blockers	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	Alpha-blockers	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
Angiotensin 2 blockers	Angiotensin 2 blockers	blood pressure	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Angiotensin 2 blockers	heart failure	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Angiotensin 2 blockers	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Angiotensin 2 blockers	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
Antihistamines	Antihistamines	allergies	0	2		1		Tapering not required	No														
	Antihistamines	unknown	2	2		1		Tapering not required															
	Antihistamines	other 	??	??		1		Tapering not required															
	ASA	osteoarthritis	2	0		1		Tapering not required	No														
	ASA	unknown	2	2		1		Tapering not required															
	ASA	other 	??	??		1		Tapering not required															
	ASA WHAT ABOUT GENERAL PAIN?	rheumatoid arthritis	0	2		1		Tapering not required	No														
Tranquilizers	Benzodiazepines	anxiety 	0	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"rebound insomnia, tremor, anxiety, as well as more serious, rare manifestations including hallucinations, seizures, and delirium"											
	Benzodiazepines	panic disorder	0	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"rebound insomnia, tremor, anxiety, as well as more serious, rare manifestations including hallucinations, seizures, and delirium"											
Hypnotics/sedatives	Benzodiazepines	insomnia	1	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"rebound insomnia, tremor, anxiety, as well as more serious, rare manifestations including hallucinations, seizures, and delirium"											
	Benzodiazepines	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"rebound insomnia, tremor, anxiety, as well as more serious, rare manifestations including hallucinations, seizures, and delirium"											
	Benzodiazepines	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"rebound insomnia, tremor, anxiety, as well as more serious, rare manifestations including hallucinations, seizures, and delirium"											
	Beta-blockers	AFIB	0	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Beta-blockers	heart failure	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Beta-blockers	previous heart attack or stroke	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Beta-blockers	angina	0	1		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Beta-blockers	migraine	0	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Beta-blockers	tremor	0	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
Beta-blockers	Beta-blockers	blood pressure	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	50%	every 1-2 weeks	"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Beta-blockers	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Beta-blockers	arrhythmia	0	?		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Beta-blockers	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Calcium antagonists other	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Calcium antagonists other	arrhythmia	0	?		1		Tapering suggestions should be discussed with a specialist	Yes	bb													
	Calcium antagonists other	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
Calcium antagonists	Calcium antagonists pines	blood pressure	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	ace		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Calcium antagonists pines	angina	0	1		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	bb		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Calcium antagonists pines	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	bb		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Calcium antagonists pines	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	bb		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
Cholinesterase inhibitors	Cholinesterase inhibitors	Alzheimer's	1	2		1		Tapering not required	No														
	Cholinesterase inhibitors	unknown	2	2		1		Tapering not required															
	Cholinesterase inhibitors	other 	??	??		1		Tapering not required															
Uric acid	Colchicine	gout	0	0		1		Tapering not required	No														
	Colchicine	unknown	2	2		1		Tapering not required															
	Colchicine	other 	??	??		1		Tapering not required															
	"Diabetes other(DPP4s, Acarbose, GLPs, Meglitinides)"	type 2 diabetes with high glucose symptoms	0	2		1		Tapering not required	No			"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	"Diabetes other(DPP4s, Acarbose, GLPs, Meglitinides)"	type 2 diabetes	2	2		1		Tapering not required	No			"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	"Diabetes other(DPP4s, Acarbose, GLPs, Meglitinides)"	other 	??	??		1		Tapering not required															
	"Diabetes other(DPP4s, Acarbose, GLPs, Meglitinides)"	unknown	2	2		1		Tapering not required															
Digoxin	Digoxin	heart failure	2	1		1		Tapering not required	Yes	like bP													
	Digoxin	arrhythmia	0	2		1		Tapering suggestions should be discussed with a specialist	Yes	like bP													
	Digoxin	unknown	2	2		1		Tapering not required	Yes	like bP													
	Digoxin	other 	??	??		1		Tapering not required	Yes	like bP													
	"Diuretics (Furosemide, Metolazone, Torsemide)"	heart failure	0	1		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	same as bp		"weight gain, swelling, shortness of breath"	weight.shortness of breath ankle edema										
	"Diuretics (Furosemide, Metolazone, Torsemide)"	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"weight gain, swelling, shortness of breath"											
	"Diuretics (Furosemide, Metolazone, Torsemide)"	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"weight gain, swelling, shortness of breath"											
Antiepileptics	"Epilepsy (Gabapentin,Phenytoin, Valproate, Carbamazepine, Others"	epilepsy	2	0		1		"Reduce dose by 10-25% every month. If seizure activity occurs, go back to approximately 75% of the previously tolerated dose."	Yes			"return of seizures, no need to measure drug levels"											
	"Epilepsy (Gabapentin,Phenytoin, Valproate, Carbamazepine, Others"	pain	1	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	25% every 1-2 weeks													
	"Epilepsy (Gabapentin,Phenytoin, Valproate, Carbamazepine, Others"	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	"Epilepsy (Gabapentin,Phenytoin, Valproate, Carbamazepine, Others"	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."															
	Glitazones	type 2 diabetes with high glucose symptoms	0	2		1		Tapering not required				"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	Glitazones	type 2 diabetes	2	2		1		Tapering not required	No			"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	Glitazones	unknown	2	2		1		Tapering not required															
	Glitazones	other 	??	??		1		Tapering not required															
Hypertension	Hypertension other	blood pressure	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Hypertension other	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Hypertension other	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes			"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Incontinence	incontinence	1	2		1																	
	Incontinence	unknown	2	2		1																	
	Incontinence	other 	??	??		1																	
	Insulin	type 1 diabetes	0	1		1		Tapering not required	don't stop			"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	Insulin	type 2 diabetes with high glucose symptoms	0	1		1		Tapering not required				"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	Insulin	type 2 diabetes	2	1		1		Tapering not required	No			"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	Insulin	unknown	2	2		1		Tapering not required															
	Insulin	other 	??	??		1		Tapering not required															
	Misoprostol	ulcer prevention	2	0		1		Tapering not required															
	Misoprostol	unknown	2	2		1		Tapering not required															
	Misoprostol	other 	??	??		1		Tapering not required															
	Niacin	no history of heart attack or stroke	2	2		1		Tapering not required	No														
	Niacin	unknown	2	2		1		Tapering not required															
	Niacin	other 	??	??		1		Tapering not required															
Nitrates	Nitrates	angina	0	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	like bP		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Nitrates	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	like bP		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Nitrates	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	like bP		"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Non-benzodiazepine sedatives	insomnia	1	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"rebound insomnia, tremor, anxiety, as well as more serious, rare manifestations including hallucinations, seizures, and delirium"											
	Non-benzodiazepine sedatives	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"rebound insomnia, tremor, anxiety, as well as more serious, rare manifestations including hallucinations, seizures, and delirium"											
	Non-benzodiazepine sedatives	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes			"rebound insomnia, tremor, anxiety, as well as more serious, rare manifestations including hallucinations, seizures, and delirium"											
Antirheumatics	NSAIDs	osteoarthritis	0	2		1		Tapering not required	No														
	NSAIDs	rheumatoid arthritis	0	2		1		Tapering not required	No														
	NSAIDs	unknown	2	2		1		Tapering not required															
	NSAIDs	other 	??	??		1		Tapering not required															
	PUT METOCLOPRAMIDE SEPARATELY - different side effects		0	2		1																	
	Raloxifene	osteoporosis/previous fracture	2	0		1		Tapering not required	No														
	Raloxifene	unknown	2	2		1		Tapering not required															
	Raloxifene	other 	??	??		1		Tapering not required															
Smoking cessation	Smoking cessation	smoking cessation	0	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	like TCA etc			"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	Smoking cessation	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	like TCA etc			"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	Smoking cessation	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	like TCA etc			"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	Sulfonylureas	type 2 diabetes with high glucose symptoms	0	1		1		Tapering not required	No			"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	Sulfonylureas	type 2 diabetes	2	1		1		Tapering not required				"symptoms of increased thirst/increased urination, re-measure A1c in 3 months, measure blood glucose only if high glucose symptoms occur/return"											
	Sulfonylureas	unknown	2	2		1		Tapering not required															
	Sulfonylureas	other 	??	??		1		Tapering not required															
	TCA	smoking cessation	0	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	Testosterone	andropause symptoms (vitality etc)	1	2		1		Tapering not required	No														
	Testosterone	unknown	2	2		1		Tapering not required															
	Testosterone	other 	??	??		1		Tapering not required															
Diuretics	Thiazides	blood pressure	2	0		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Thiazides	unknown	2	2		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
	Thiazides	other 	??	??		1		"If used daily for more than 3-4 weeks. Reduce dose by 50% every 1 to 2 weeks. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"chest pain, pounding heart, heart rate, blood pressure (re-measure for up to 6 months), anxiety, tremor"											
Vitamins/supplements	Vitamins/supplements	actual vitamin deficiency	0	0		1		Tapering not required	No														
	Vitamins/supplements	prevention vitamin deficiency	2	2		1		Tapering not required	No														
	Vitamins/supplements	unknown	2	2		1		Tapering not required															
	Vitamins/supplements	other 	??	??		1		Tapering not required															
Weight loss	Weight loss	weight loss	1	2		1		Tapering not required	No														
	Xanthine oxidase inhibitors(allopurinol/febuxostat)	gout	2	2		1		Tapering not required	No				gouty attacks???										
Antiarrhythmics	Antiarrhythmics	arrhythmia	1	1		2		Tapering suggestions should be discussed with a specialist	amiodarone no taper suggest done in conjunction with cardi if uncomfortable														
	Antiarrhythmics	unknown	2	2		2		Tapering suggestions should be discussed with a specialist															
	Antiarrhythmics	other 	??	??		2		Tapering suggestions should be discussed with a specialist															
	Biologics	unknown	2	2		2		Tapering suggestions should be discussed with a specialist															
	Biologics	other 	??	??		2		Tapering suggestions should be discussed with a specialist															
	Biologics	rheumatoid arthritis	0	1		2		Tapering suggestions should be discussed with a specialist	ASK SPECIALIST														
Corticosteroids	Corticosteroids	inflammatory conditions	0	1		2		"If used daily for more than 3-4 weeks. Reduce dose by 5mg/week until 10 mg/day is reached. Subsequent dosages should be decreased by 2.5mg/week until the medication is stopped. If withdrawal symptoms occur, increase the dosage and taper at 1mg/week."	Yes			"weakness, fatigue, decreased appetite, weight loss, nausea, vomiting, diarrhea, constipation, abdominal pain, low blood pressure, low blood glucose, joint pain, muscle aches, fever, mental changes"											
	Corticosteroids	unknown	2	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 5mg/week until 10 mg/day is reached. Subsequent dosages should be decreased by 2.5mg/week until the medication is stopped. If withdrawal symptoms occur, increase the dosage and taper at 1mg/week."				"weakness, fatigue, decreased appetite, weight loss, nausea, vomiting, diarrhea, constipation, abdominal pain, low blood pressure, low blood glucose, joint pain, muscle aches, fever, mental changes"											
	Corticosteroids	other 	??	??		2		"If used daily for more than 3-4 weeks. Reduce dose by 5mg/week until 10 mg/day is reached. Subsequent dosages should be decreased by 2.5mg/week until the medication is stopped. If withdrawal symptoms occur, increase the dosage and taper at 1mg/week."				"weakness, fatigue, decreased appetite, weight loss, nausea, vomiting, diarrhea, constipation, abdominal pain, low blood pressure, low blood glucose, joint pain, muscle aches, fever, mental changes"											
	Depression other	unknown	2	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."															
	Depression other	other 	??	??		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."															
	Depression other	depression	1			2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes														
Antipsychotics	First generation antipsychotics	agitation in dementia	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	First generation antipsychotics	bipolar	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	First generation antipsychotics	depression	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	First generation antipsychotics	schizophrenia	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	First generation antipsychotics	unknown	2	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	First generation antipsychotics	other 	??	??		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
Narcotics	Narcotics	pain	0	2		2		"If used daily for more than 3-4 weeks. Reduce the dose by 25% every 3 to 4 days. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	10-25%	every week	"restlessness, runny nose, goose flesh, sweating, muscle cramps, insomnia, nausea, diarrhea, pain, secretion of tears, increased heart rate, dilation of the pupils, breathlessness, decrease or impairment in daily function"	"pain, withdrawal, agitation, goose flesh, GI upset, titrate laxatives down as needed"										
	Narcotics	shortness of breath in end-stage illness	0	2		2		"If used daily for more than 3-4 weeks. Reduce the dose by 25% every 3 to 4 days. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."	Yes	10-25%	every week	"restlessness, runny nose, goose flesh, sweating, muscle cramps, insomnia, nausea, diarrhea, pain, secretion of tears, increased heart rate, dilation of the pupils, breathlessness, decrease or impairment in daily function"	"pain, withdrawal, agitation, goose flesh, GI upset, titrate laxatives down as needed"										
	Narcotics	unknown	2	2		2		"If used daily for more than 3-4 weeks. Reduce the dose by 25% every 3 to 4 days. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"restlessness, runny nose, goose flesh, sweating, muscle cramps, insomnia, nausea, diarrhea, pain, secretion of tears, increased heart rate, dilation of the pupils, breathlessness, decrease or impairment in daily function"											
	Narcotics	other 	??	??		2		"If used daily for more than 3-4 weeks. Reduce the dose by 25% every 3 to 4 days. Once at 25% of the original dose and no withdrawal symptoms have been seen, stop the drug. If any withdrawal symptoms occur, go back to approximately 75% of the previously tolerated dose."				"restlessness, runny nose, goose flesh, sweating, muscle cramps, insomnia, nausea, diarrhea, pain, secretion of tears, increased heart rate, dilation of the pupils, breathlessness, decrease or impairment in daily function"											
	NOAC	afib/valve	2	0		2		Tapering not required	No														
	NOAC	unknown	2	2		2		Tapering not required															
	NOAC	other 	??	??		2		Tapering not required															
	Second generation antipsychotics	agitation in dementia	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	Second generation antipsychotics	bipolar	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	Second generation antipsychotics	depression	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	Second generation antipsychotics	schizophrenia	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	Second generation antipsychotics	unknown	2	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	Second generation antipsychotics	other 	??	??		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."				"agitation, activation, insomnia, rebound psychosis, withdrawal-emergent abnormal movements, nausea, feeling of discomfort, sweating, vomiting, insomnia – these symptoms vary somewhat depending on the specific antipsychotic"											
	SNRI	anxiety 	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SNRI	chronic pain	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SNRI	depression	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SNRI	obsessive compulsive disorder	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SNRI	unknown	2	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SNRI	other 	??	??		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SSRI	anxiety 	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
Antidepressants	SSRI	depression	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	"25-50Initial for two weeks - then let patients help decide - if no problems with first couple of dosage reductions down to 25% - then can stop, - if they start to get symptoms before this available by phone  "		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SSRI	obsessive compulsive disorder	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SSRI	chronic pain	2	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SSRI	unknown	2	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	SSRI	other 	??	??		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"nausea, diarrhea, abdominal pain, sweating, headache, dizziness, cold and flu-like symptoms, anxiety, irritability, trouble sleeping, unusual sensory experiences (e.g. electric shock-like feelings, visual after images), sound and light sensitivity, muscle aches and pains, chills, confusion, pounding heart (palpitations), unusual movements, mood changes, agitation, distress, restlessness, rarely suicidal ideation"											
	TCA	anxiety 	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	TCA	chronic pain	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	TCA	depression	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	TCA	insomnia	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	TCA	obsessive compulsive disorder	1	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	TCA	unknown	2	2		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
	TCA	other 	??	??		2		"If used daily for more than 3-4 weeks. Reduce dose by 25% every week (i.e. week 1-75%, week 2-50%, week 3-25%) and this can be extended or decreased (10% dose reductions) if needed. If intolerable withdrawal symptoms occur (usually 1-3 days after a dose change), go back to the previously tolerated dose until symptoms resolve and plan for a more gradual taper with the patient. Dose reduction may need to slow down as one gets to smaller doses (i.e. 25% of the original dose). Overall, the rate of discontinuation needs to be controlled by the person taking the medication."	Yes	AS SSRI		"cramping, diarrhea, nausea, sweating, hot or cold flashes, headache, dizziness, flu-like symptoms, fatigue, anxiety, restlessness, trouble sleeping, vivid dreams, tremors, muscle aches, confusion, pounding heart (palpitations), unusual movements, mood changes"											
Anti-clotting	Warfarin	afib/valve	2	0		2		Tapering not required	No														
	Warfarin	unknown	2	2		2		Tapering not required															
	Warfarin	other 	??	??		2		Tapering not required															
IBD	IBD	inflammatory bowel disease	0	1		?		Tapering not required	No														
	Migraine other	migraine	?	?		?																	
Antinausea	Nausea	nausea	0	2		?			No	if get symptoms change													
Parkinson's	Parkinson's FIX	Parkinson's	?	?		?																	
	Diarrhea	unknown	2	2																			
	Diarrhea	other 	??	??																			
	IBD	unknown	2	2				Tapering not required															
	IBD	other 	??	??				Tapering not required															
	Migraine other	unknown	2	2																			
	Migraine other	other 	??	??																			
	Nausea	unknown	2	2																			
	Nausea	other 	??	??																			
	Osteoporosis other	osteoporosis/previous fracture	2	0				Tapering not required	No														
	Osteoporosis other	unknown	2	2				Tapering not required															
	Osteoporosis other	other 	??	??				Tapering not required															
	Parkinson's FIX	unknown	2	2																			
	Parkinson's FIX	other 	??	??																			
	PUT METOCLOPRAMIDE SEPARATELY - different side effects	unknown	2	2																			
	PUT METOCLOPRAMIDE SEPARATELY - different side effects	other 	??	??																			
	Xanthine oxidase inhibitors(allopurinol/febuxostat)	unknown	2	2				Tapering not required															
	Xanthine oxidase inhibitors(allopurinol/febuxostat)	other 	??	??				Tapering not required															
		FIBROMYALGIA - ??MIKE								AS SSRI													
																							
	Dimenhydrinate for NAUSEA