TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 177: The evidence around the health benefits of coffee and organic foods

In episode 177, Mike and James, both high as a kite on caffeine, discuss the health benefit evidence around coffee ingestion and also discus the evidence or lack thereof of the heath issues around the use of organic foods. At the end we come to the conclusion that ketchup is really the quintessential food and decide that it goes well with everything.

1) Association of Coffee Drinking with Total and Cause-Specific Mortality

Largest cohort N Engl J Med 2012;366:1891-1904


Ann Intern Med 2008;148:904-914

Eur J Epidemiol 2011 ;26:285-93

J Nutr 2010;140:1007-13

Br J Nutr 2008;99:1354-61

Diabetologia 2006;49:2618–2626

Diabetologia 2009;52:810–817

Arch Intern Med 1978;138:1472-5

Ann Epidemiol 1993;3:375-81

BMC Cancer 2011;11:96

Ann Oncol 2011;22:536-44

BJU Int 2010;106:762-9

Ann Oncol 2012;23:311-8 

J Natl Cancer Inst 2010;102:771–783 

J Epidemiol Community Health 2011;65:230-40

Am J Epidemiol 2011;174:993–1001 

Arch Intern Med 2000;160:3393-3400 

Arch Intern Med 2009;169:2053-2063

Arch Intern Med 2011;171:1571-1578

BMJ 2003 Feb 22;326:420

2) Are Organic Foods Safer or Healthier Than Conventional Alternatives?

Ann Intern Med 2012;157:348-66

3) TEC podcast survey link – PLEASE GIVE IT A GO


Episode 176: Hormonal contraception – does it give birth to thromboembolic complications?

In episode 176, we get back to a non-PREMIUM podcast and discuss the evidence around the venous thromboembolism risk associated with different types of hormonal contraception. In our ongoing desire to provide our podcast listeners with solid information both Mike and James started taking oral contraceptives a few years ago and they are glad to report that neither have developed any side effects (at least that they are willing to discuss) and, believe it or not, neither of them have become pregnant.

Show notes

1) What are the Venous Thromboembolism risks with varying Hormonal Contraception?

Tools for Practice

Episode 175: PREMIUM Pyelonephritis and type 2-diabetes – keep changing your previously held beliefs

In episode 175, James and Mike discuss even more PREMIUM practice changing articles. We find out that pyelonephritis only needs 7 days of treatment and the new diabetes guidelines are finally changing to match the evidence – but you already heard the evidence on this from us when it first came out 2-3 years ago.

Show notes

1) 7 versus 14 days for pyelonephritis

Lancet 2012;380:484–90

2) New diabetes guidelines – finally a change

Diabetes Care 2012;35:1364-79

Episode 174: PREMIUM Is salt the spice of life and sitting on the fence about PSA screening

In episode 174, Mike and James discuss some PREMIUM practice changing articles around heart failure and salt and the quality of life associated with PSA screening. At the end we have a meal of chips, pickles, Big Macs, and salami to celebrate the completion of yet another PREMIUM podcast.

Show notes

1) Low sodium versus normal sodium diets 

Systolic heart failure

Heart 2012 doi:10.1136/heartjnl-2012-302337

Non-heart failure

Am J Hypertens 2011;24:843-53

2) Quality-of-life effects of prostate-specific antigen screening

N Engl J Med 2012;367:595-605

3) Furthering the prostate cancer screening debate (prostate cancer specific mortality and associated risks)

Can Urol Assoc J 2011;5:416–21


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Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.


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