TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 283: PREMIUM – Glucose, blood pressure and statin studies to the max

In episode 283, Mike and James discuss the latest T2DM study showing that sitagliptin at least doesn’t cause much harm. We then veer off to discuss everything you need to know about diastolic and systolic blood pressure and how are they associated with CVD. Finally we discuss an n-of-1 study looking at statin-related myalgia. Bottom line – this was clearly a PREMIUM podcast.

Show notes

1) TECOS – Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes

N Engl J Med 2015; 373:232-242

2) Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

Lancet 2014;383:1899-1911

3) N-of-1 (Single-Patient) Trials for Statin-Related Myalgia

Ann Intern Med 2014;160:301-310

Episode 281: Bedtime restriction instead of pills for primary insomnia

In episode 281, James and Mike welcome back our friend and colleague Bruce Arroll to talk about a great study he and his colleagues recently completed looking at simple bedtime restriction for the treatment of primary insomnia – and the results were pretty impressive. So much so that Bruce had to wake us both up at the end of the podcast.

Show notes

1) Development, validation (diagnostic accuracy) and audit of the Auckland Sleep Questionnaire: a new tool for diagnosing causes of sleep disorders in primary care

2) A double-blind randomised controlled study of a brief intervention of bedtime restriction for adult patients with primary insomnia 

See List of All Podcast Episodes


BS Medicine Podcast

The 2024 MEME Conference – May 24-25, 2024


Making Evidence Matter For Everyone | May 24 & 25, 2024
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice




Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.


BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

PEER Tools


Recent Posts