In episode 459, James and Mike invite Mike Kolber to talk about whether or not the increased rate of colorectal cancer in people under 50 means we should be screening earlier. We talk about all the numbers and put the risk into the context of the absolute numbers.

Show notes 

1) Tools for Practice

In episode 458, James and Mike finally get back to being PREMIUM and cover a number of new and useful RCTs. We discuss 4 new Vitamin D trials, atrial fibrillation and do you need both rate and rhythm control, swollen legs and cellulitis, and is colchicine the new statin. Check out the PREMIUM podcast for all the answers.

Show notes 

In episode 457, James and Mike yet again invite Joey Ton to go through the evidence around reaching a target serum urate level in patients with gout. As with many arbitrary thresholds determined from observational studies (sometimes), or just made up, when you properly study if there is a benefit to achieving these levels the theory really crumbles under the weight of the evidence.

In episode 456, James and Mike and Nic continue to go through all the evidence (primarily RCTs) around the use of masks and reducing the risk for viral illnesses. In this episode we talk about our systematic review and what we found for the public. Please also check out our simplified tool that describes all the information we found.

Show notes 

In episode 455, James and Mike invite Nic Dugré to go through all the evidence (primarily RCTs) around the use of masks and reducing the risk for viral illnesses for both healthcare workers and the public. In this episode we talk about our systematic review and what we found for healthcare workers - the following episode will be about the general public.

In episode 454, James and Mike invite Adam Keough to go through all the evidence around the impact of long-term running. We find out that recreational running likely does not increase the risk of developing osteoarthritis but high-level elite athletes may have an increased risk. Interestingly, exercise is one of the most effective treatments for reducing osteoarthritic pain.

In episode 453, James and Mike invite Jessica Kirkwood to go over all the evidence for transitioning infants to solid foods using a baby-led weaning approach versus traditional spoon feeding. Overall, it really didn’t make much difference which approach was used. But listen to hear us take a bite out of all the nuances and context.

Show notes 

In episode 452, James and Mike go over 2 recent publications which encapsulate all the important evidence around type 2 diabetes. We talk about the misdirection that occurs with T2DM evidence versus what we do in practice. We now have all the evidence and we know what these medications do or don’t do to important clinical endpoints. Could we please use this information when we treat T2DM.