In episode 432, James and Mike finish their review of the evidence around medications for systolic heart failure. In this episode our goal was to try to make sense of the process by adding as much art as possible to the evidence and also use a modicum of common sense. Let us know if we achieved our goal.

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In episode 431, James and Mike continue their review of the evidence around medications for systolic heart failure. In this episode we discuss betablockers, ACEIs, ARBs, MRAs and a few other key trials of somewhat newer agents. 

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In episode 430, James and Mike do a review of all the best available evidence around medications for systolic heart failure. In this episode we start off by framing the risk associated with heart failure (mortality and hospitalizations for heart failure) and what the evidence is for exercise, salt, diuretics, digoxin and ISDN/hydralazine.

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In episode 429, Mike and James continue their discussion with Barb Farrell around deprescribing. We talk in generalities, with occasional brilliant specificity, about the PPI/benzos/antipsychotics/glucose lowering medication deprescribing guidelines. In the end we come up with the astounding idea that maybe some people are on too many medications.

In episode 428, Mike and James invite Barb Farrell to discuss all the great work being done by the people at deprescribing.org.  We discuss the general approach to deprescribing and why it is so important to keep this concept front and center of health discussions.

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In episode 427, James and Mike invite Mark McConnell back to the podcast to discuss the philosophy around how not to do what didn’t need to be done. You start with a differential diagnosis then think about what are the possible causes of this presentation?

In episode 426, James and Mike discuss in a PREMIUM way the first large RCT of the polypill. This single pill version contained aspirin, atorvastatin, hydrochlorothiazide, and either enalapril or valsartan. Have a listen and find out what happened.

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In episode 425, James and Mike invite Samantha back again to talk about the evidence around the incidence of opioid use disorder that we cause by prescribing opioids. The key issue seems to be whether or not your patient has a history of substance abuse. 

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Tools For Practice