In episode 345, Mike and James enlist Adrienne Lindblad to help us go through the tricky topic of taking medications in pregnancy. Adrienne covers the topic in general and then discusses some of the evidence around medications for nausea and vomiting around pregnancy.

Show notes

In episode 344, Mike and James discuss the impact of giving fish oil supplementation to reduce the chance of allergic disease in children. The results are consistently inconsistent which leaves us both kind of itching for the truth.

Show notes

Tools for Practice

In episode 343, Mike and James talk about a paper they recently published about how we need to think about confidence intervals and how one can think overall about the results of clinical trials. The bottom line is to be more pragmatic and less dogmatic and remember the answers are rarely yes and no.

Show notes

In episode 342, James and Mike talk about yet another Vitamin D meta-analysis and explain why it really changes nothing when it comes to Vitamin D. But then we talk about a novel RCT on ultrasound treatment for serious hand tremor and it makes us shake all over.

Show notes

In episode 341, James and Mike talk about the long awaited trial of evolocumab that evaluated the impact it has on cardiovascular outcomes. Certainly not a homerun - maybe a very expensive full swing bunt with an error that leads to a single. 

Show notes

1) Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease 

In episode 340, Mike and James get all bent out of shape when they discuss the evidence around spinal manipulative therapy and low back pain. The evidence suggests no reliable effect for acute pain but the possibility of an effect for chronic pain. But any recommendations are a stretch because of the poor quality of the evidence.

Show notes

In episode 339, Mike and James talk about the evidence that has do with do with whether you need to use sterile gloves and saline for excisions and lacerations. The answer is that you should insert a suppository with the non-tapered end first.  Listen to the podcast and see how we come to that conclusion.

Show notes

1) Tools for practice

In episode 338, Tina, Mike and James go over the best available evidence around the treatment for recurrent vulvovaginal candidiasis and we find that we can reduce relapse with regular use of azole antifungals or we could just treat when symptoms occur – guess what, it’s all up to patient preference. Oh, and treating the partner makes no difference.

Show notes