Episode 9: News Flash: Aggressive Blood Sugar Control Not All Sweet
In our ninth episode, we interrupt our regularly scheduled podcast to talk about the recently released ACCORD and ADVANCE trials which focus on intensive glucose control (reduction) in diabetes. We discuss the patient-oriented outcomes and harms, ranging from mortality to hypoglycemia, as well as the potential benefits such as preventing microalbuminuria. Evidence regarding patient blood sugar monitoring is reviewed while reminding listeners how much fun monitoring is for our patients.
1) A synopsis of what was reported in the ACCORD and ADVANCE studies.
N Engl J Med 2008 358:2545-2559
N Engl J Med 2008 358:2560-2572
2) Studies of monitoring blood sugar in type 2 diabetics showing no benefit and increased depression scores
BMJ. 2007 Jul 21;335(7611):105-6