TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 435: Unwrapping the subclinical hypothyroidism enigma

In episode 435, Mike and James unravel the evidence around thyroid testing. We talk about an approach to deal with the lack of research and the variation in the measurement of TSH and many other things. At the end we both complain of fatigue, dry skin, puffy eyes, anxiety and depression – and immediately get a TSH test.

Show notes

1) Tools for Practice

Helping physicians fatigued by TSH Screening and Subclinical Hypothyroidism

2) Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline

BMJ. 2019 May 14;365:l2006. doi: 10.1136/bmj.l2006

Episode 434: PREMIUM – finally, an LDL target trial

In episode 434, James and Mike discuss the Treat Stroke to Target trial where subjects were randomized to attain different LDL levels in patients experiencing a stroke or TIA. We talk about whether the results of this trial mean you need to measure LDL levels or just give more statin. Listen to find out.

Show notes

A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke

N Engl J Med. 2019 Nov 18. doi: 10.1056/NEJMoa1910355

Episode 433: Yes, more diabetes trials

In episode 433, Mike and James get all sweet on the latest diabetic trials from 2019. We provide the results, the critique and the context and we do it all with our usual level of charm and wit – which is by all accounts at a level similar to the size of the effect that many diabetes medications have on CVD events. 

Show notes

Diabetes trials synopsis

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BIG ANNOUNCEMENTS

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

THE MEME CONFERENCE – Making Evidence Matter For Everyone

May 27-28, 2022 in Vancouver, BC

Our annual primary care evidence-based conference is BACK. The MEME conference is happening May 27/28 live and virtual in beautiful Vancouver, BC. Sure hope you can join us.

REGISTER NOW

BS Medicine Podcast

BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

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