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Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 371: Back to listener questions – finally

In episode 371, James and Mike get back to listener question. We talk about iron, TPA, big blood pressure numbers, antipsychotics and lab measurements. Hopefully we leave the audience with more answers than questions.

Show notes

1) Are we giving too much iron? Low-dose iron therapy is effective in octogenarians

Am J Med 2005;118:1142-7

2) Clot – dissolving drugs for treating ischaemic stroke in the early stages

Cochrane Review

3) Effect of Propranolol In Mild Hypertension

Lancet 1966;288:1148–50

4) Head-to-head comparisons of metabolic side effects of second-generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis

Schizophr Res 2010;123:225-33

5) Chronic Kidney Disease (CKD) Clinical Pathway

Episode 370: PREMIUM – Back pain, knee pain, fractures and skin abscesses

In episode 370, Mike and James decide to follow their New Year’s resolution by trying to present some new studies in a useful and thoughtful way – in other words, a PREMIUM podcast. We talk about a trial of pregabalin for sciata, a trial of intra-articular steroid injections for knee pain, romosozumab/alendronate for fractures and antibiotics for small abscesses.

Show notes

1) Trial of Pregabalin for Acute and Chronic Sciatica

N Engl J Med 2017;376:1111-20

2) Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial

JAMA 2017;317:1967-75

3) Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis

N Engl J Med 2017; 377:1417-27

4) A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses

N Engl J Med 2017;376:2545-55

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BedMed: The High Blood Pressure Study

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