TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 526: PREMIUM – The latest on salt and vitamins

In episode 526, Mike and James go PREMIUM yet again, although it takes a while – so stay till the end. We go over the latest research on low sodium in heart failure, Vitamin D for preventing COVID, and multivitamins for doing anything. Show Notes 1) Reduction of dietary sodium to less than 100 mmol…

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Episode 525: Weight – the evidence may be slimmer than you think – PART II

In episode 525 – part two of our series on weight – James and Mike talk about how best to measure “weight” – and waste circumference, and hip -to-weight ratio and so on. We show that there is very little reason to measure much else other than actual weight. We also look at the evidence around whether intentional weight loss improves outcomes. Bariatric surgery evidence is also reviewed. And also a few other gems of knowledge.

Show Notes
1) The Nutrition Proposition
Book website
nutritionproposition.com

 Amazon Link

2) Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies
Lancet. 2011;377(9784):1085-1095. doi:10.1016/s0140-6736(11)60105-0
3) Central fatness and risk of all-cause mortality: systematic review and dose-response meta-analysis of 72 prospective cohort studies
Bmj. 2020;370:m3324. doi:10.1136/bmj.m3324
4) Discriminatory Capacity of Anthropometric Indices for Cardiovascular Disease in Adults: A Systematic Review and Meta-Analysis
Prev Chronic Dis. 2020;17:E131. doi:10.5888/pcd17.200112

5) A systematic review of reviews: exploring the relationship between obesity, weight loss and health-related quality of life
Clinical Obesity 7, 273–289, October 2017

6) Effectiveness of Weight-Loss Interventions for Reducing Pain and Disability in People With Common Musculoskeletal Disorders: A Systematic Review With Meta-Analysis
J Orthop Sports Phys Ther 2020;50(6):319–333. Epub 9 Apr 2020. doi:10.2519/jospt.2020.9041

Episode 524: Weight – the evidence may be slimmer than you think

In episode 524 – the first of a 2-part series about weight – James and Mike talk about why people wish to lose weight, the words we use to describe weight, the obesity paradox, all the cohort evidence around weight and mortality/cardiovascular disease/depression/osteoarthritis/fractures, and in a nice juxtaposition do it while eating rum and raisin ice cream – yes it is a thing.

Show Notes
1) The Nutrition Proposition
Book website

Amazon Link

2) In their own words: Topic analysis of the motivations and strategies of over 6,000 long‐term weight‐loss maintainers
Obesity (Silver Spring). 2022;30:751–7614)

3) Patients’ preferred terms for describing their excess weight: discussing obesity in clinical practice
Obesity (Silver Spring). 2012;20(1):147–50

Episode 523: Is booking an urgent UTI appointment the best sign of a UTI?

In episode 523, James and Mike invite Jennifer Young to the podcast for the first time to help us go over all the evidence around diagnosing symptomatic uncomplicated urinary tract infections in adult women. We also delve into the “fun“ world of likelihood ratios – believe it or not, they are REALLY useful. So hang on to your hat!

Show Notes
Tools for Practice
Is booking an urgent UTI appointment the best sign of a UTI?

Episode 521: A dose a day keeps the UTI away?

In episode 521, James and Mike invite Caitlin Finley to the podcast for the first time to talk about a very common primary care topic – recurrent UTIs. We discuss the frequency of recurrence and look at the evidence for many of the different strategies used to reduce the chance of recurrence.

Show Notes
1) Tools for practice
A dose a day keeps the UTI away?

2) PRACTICAL EVIDENCE FOR INFORMED PRACTICE (PEIP) CONFERENCE 2022
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Episode 519: Oh Baby – Combined oral contraceptives during breastfeeding

In episode 519, Mike and James ask Jen Potter back to the podcast to talk about a common primary care question around oral contraceptives and breast feeding. We review the best available evidence which unfortunately we find out is not the highest quality. Nonetheless, we go over the numbers and then come up with useful, hopefully, suggestions for what to do around this issue.

Show Notes
Tools for Practice
Oh Baby: Combined oral contraceptives during breastfeeding

Episode 518: Avoiding lactose-containing products during acute pediatric diarrhea

In episode 518, Mike and James get Samantha to go through all the evidence we have for restricting lactose-containing foods in children with acute diarrhea. While we find out that looking at this evidence is at best tricky, it seems like reducing or diluting formula may provide a reasonable benefit. Listen to the podcast for the numbers.

Show Notes
Tools for Practice
“Not Milk?”: Avoiding lactose-containing products during acute pediatric diarrhea

Episode 516: The LARC (long-acting reversible contraception) Song: Is the etonogestrel implant a hit?

In episode 516, James and Mike invite Nicolas Dugré to the podcast yet again, and this time we talk about the evidence around the latest long-acting implantable reversible contraception. As always, we talk about the efficacy, the harm and all the rest of the issues around the use of these forms of contraception.

Show Notes

Tools For Practice
The LARC (long-acting reversible contraception) Song: Is the etonogestrel implant a hit?

Check out the Pharmascope Podcast – The French “version” of the BS Medicine Podcast

Episode 515: Weight to Go: Naltrexone/bupropion for weight loss

In episode 515, James and Mike invite Allison Paige to the podcast for the first time. Alli takes us through all the evidence around a combination product (naltrexone/bupropion) for weight loss. We talk about all the numbers we have for benefit, harm and cost and we put this agent into the context of the other medications we use for weight loss.

Show Notes

Tools For Practice

Weight to Go: Naltrexone/bupropion for weight loss

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BS Medicine Podcast

MEME 2023 Conference May 12-13, 2023

Making Evidence Matter For Everyone | May 12 & 13, 2023
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice

hectalks.com

BIG ANNOUNCEMENT

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

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