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Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 306: Flibanserin: Feeling frisky or falling over?

In episode 306, Mike and James engage Tina in a discussion on the first medication approved specifically for female sexual dysfunction.  She titillates us with the FDA approval stories and the evidence behind the use of this agent.

Show note

 1) Tools For Practice

Flibanserin: Feeling frisky or falling over? 

2) Efficacy and Safety of Flibanserin for the Treatment of Hypoactive Sexual Desire Disorder in Women: A Systematic Review and Meta-Analysis

JAMA Intern Med. 2016 Feb 29. doi: 10.1001/jamainternmed.2015.8565


Hi Everyone – our website had not been updated in a number of years and over the last few months we decided to upgrade the website to improve functionality. Two weeks ago we launched the revised site and despite a lot of testing etc before launch it has not functioned well at all. MY SINCERE APOLOGIES. For that reason we have, for the time being, reverted back to the old site and hopefully things will function the way they did previously.

Thanks to everyone who let us know of the issues and for everyone’s patience.


PS – I would like to blame Mike but he had nothing to do with this problem 🙂 

Episode 304: Lipid guidelines done by primary care clinicians – FINALLY

In episode 304, Mike and James describe the Simplified Lipid Guidelines, a document developed primarily by primary care clinicians that puts common sense at the forefront. Importantly, instead of thresholds for treatment we talk about thresholds for discussions – a fundamentally big difference.

Show notes

Simplified lipid guidelines – Prevention and management of cardiovascular disease in primary care

Canadian Family Physician 2015;61:857-67

Episode 303: PREMIUM – Blood pressure, back pain, and chlamydia

In episode 303, James and Mike finally get back into PREMIUM mode. We discuss two new hypertension meta-analyses that help clarify (at least somewhat) what we can be discussing with patients. In addition, we discuss a great new study on acute back pain and whether or not we should add a narcotic or a muscle relaxant and one study on what to use for chlamydia. You can’t get any more PREMIUM than that.

Show notes

1) Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses

BMJ 2016;352:i717

2) Effects of blood pressure lowering on outcome incidence in hypertension: 7. Effects of more vs. less intensive blood pressure lowering and different achieved blood pressure levels – updated overview and meta-analyses of randomized trials

Journal of Hypertension 2016, 34:000–000 

3) Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain

JAMA 2015;314:1572-80

4) Azithromycin versus Doxycycline for Urogenital Chlamydia trachomatis Infection 

N Engl J Med 2015;373:2512-21

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BS Medicine Podcast

The 2024 MEME Conference – May 24-25, 2024


Making Evidence Matter For Everyone | May 24 & 25, 2024
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice




Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.


BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

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