Episode 343: Confidently speaking about how to confidently understand confidence intervals
In episode 343, Mike and James talk about a paper they recently published about how we need to think about confidence intervals and how one can think overall about the results of clinical trials. The bottom line is to be more pragmatic and less dogmatic and remember the answers are rarely yes and no.
Are potentially clinically meaningful benefits misinterpreted in cardiovascular randomized trials? A systematic examination of statistical significance, clinical significance, and authors’ conclusions.
BMC Med. 2017 Mar 20;15(1):58. doi: 10.1186/s12916-017-0821-9