TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 191: A New Year brings new questions and some new but mainly old answers – PART III

In episode 191, Mike and James finally get to the end of the latest listener questions. We try our best to answer issues about niacin, insulin, COPD, hypertension and most importantly sputum color. At the end we also question the questioner’s questions, which leads us to even more questioning.

Show notes

1) Two studies of niacin


N Engl J Med 2011;365:2255-67



2) Tools for Practice

The long and short of long acting insulin analogues (versus NPH)?

3) Sputum color

Eur Respir J 2012;39:1354–60


N Engl J Med 2008;358:1887-98

5) Tools for practice

Can Fam Phys 2010;56:1141

5) Chorthalidone versus hydrochlorothiazide

Hypertension 2012;59:1110-7

6) 150 SBP vs 140 SBP

Hypertension 2010;56:196-202

Episode 190: A New Year brings new questions and some new but mainly old answers – PART II

In episode 190, James and Mike answer questions about the zoster vaccine, the flu vaccine, then we shift to estrogen and diabetes and finally discuss something that is not controversial at all, the HPV vaccine.

Show notes

1) Flu vaccine controversy

Center for Infectious Disease Research and Policy 

2) New hormone replacement trial

BMJ 2012;345:e6409. doi: 10.1136/bmj.e6409 

3) Statins and glucose

J Invest Med 2009 57:495-9

Episode 189: A New Year brings new questions and some new but mainly old answers

In episode 189, James and Mike start off the New Year by briefly discussing the results of the TEC podcast survey. We then delve into some great listener questions. We talk about BMI, diabetes, antibiotic duration, statins etc and provide some great podcast answers. At the end we both drink champagne and get a little giddy – but we doubt anyone will notice.

Show notes

1) Niacin – yet another negative study


2) Coenzyme Q10 supplementation for statin-induced myalgias

Am J Cardiol 2012;110:526–9

3) Association of an Intensive Lifestyle Intervention With Remission of Type-2 Diabetes – LookAHEAD

JAMA 2012;308:2489-96. doi:10.1001/jama.2012.67929

4) New BMI study

 JAMA 2013;309:71-82

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