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Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 147: Definitively vague questions with vaguely definitive answers

In episode 147, Mike and James cover the issue of humor in teaching, put drugectomies in LTC facilities into perspective, discuss the use of antibiotics in COPD, and finally contextualize bisphophonates and estrogen for fracture reduction. At the end they agree that the 30 minutes of podcast excellence should leave the audience laughing and crying but not for the right reasons.

Show notes

1) Chronic antibiotics in COPD

Am J Respir Crit Care Med 2008;178:1139-47

N Engl J Med 2011;365:689-98

2) Bisphosphonates/zoledronic acid

BMC Musculoskeletal Disorders 2011,12:209

N Engl J Med 2007; 356:1809-1822

3) Lower doses of estrogen

Fertil Steril 2001;75:1065-79

Episode 146: PREMIUM Two potentially practice changing studies

In episode 146, a PREMIUM podcast, Mike and James talk about some timely studies. Mike discusses some interesting results from a study that looked at the simple intervention of taking antihypertensives at bedtime and we find out that this intervention not only has an impact on blood pressure but also produces a further reduction in cardiovascular events. James then discusses the latest atrial fibrillation study which looked at what happens to cardiovascular events when you compare warfarin to apixaban. 


1) Taking antihypertensives at bedtime

Chronobiology International 2010;27:1629–51

2) Apixaban versus warfarin in patients with atrial fibrillation

N Engl J Med 2011;365:981-92

Episode 145: Don't get fooled again and again – New Zealand September 2011

In episode 145, Mike and James bring you, live on-tape from down-under, our presentation at the 2011 Conference for General Practice in New Zealand. We talk about why most new things aren’t much if any better and then discuss the issue of things like surrogate markers, physiological mechanisms, meta-analyses, selective publication/reporting, measurement/scales and “Risky” superlatives.

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11th Annual PEIP Conference October 21-22, 2022

Practical Evidence for Informed Practice Conference | October 21 & 22, 2022
Led by the team that brings you Tools for Practice, the Practical Evidence for
Informed Practice (PEIP) Conference brings together clinical leaders to speak on
the latest findings that can affect how you practice.




Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.


BS Medicine Podcast

BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

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