TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 555: An ASA a day when a baby’s on the way?

In episode 555, James and Mike invite Jamie Falk back to the podcast to talk about the best available evidence for acetylsalicylic acid and its potential impact on reducing the risk of complications in women at risk of preeclampsia. The evidence is pretty clear and we are able to give decent estimates of the benefits and harms. Have a listen – it may change your practice.

Show notes

Tools for Practice
An ASA a day when a baby’s on the way?

Episode 554: Stress Urinary Incontinence: Pelvic floor exercises or pessary?

In episode 554, James and Mike go over a topic we have never covered in 553 previous podcasts. We invited Samantha Moe back to the podcast to talk about how effective are pelvic floor exercises or pessaries for stress urinary incontinence. We find that the magnitude of the benefits from pelvic floor exercises is fairly impressive. Tune in to find out what numbers we thought justified the phrase “fairly impressive” and see if you agree.

Show notes

Tools for Practice
Stress Urinary Incontinence: Pelvic floor exercises or pessary?

Episode 553: How to Slow the Flow – Tranexamic acid for heavy menstrual bleeding

In episode 553, James and Mike get Jen Potter back to talk about the last option we have for heavy menstrual bleeding – tranexamic acid. We talk about how it compares to placebo, NSAIDs, progestins and levonorgestrel intrauterine devices and go over all the numbers for benefits and harms. And then as always, we put everything into clinical context.

Show notes

1) How to Slow the Flow III: Tranexamic acid for heavy menstrual bleeding

Tools for Practice

2) Updated Simplified Lipid Guideline 2023

3) CFPC Learn

 

Episode 552: A free PREMIUM podcast – HTN and HF

In episode 552, James and Mike go over a couple of new trials. We talk about a blood pressure trial that examined taking the pills in the morning vs the evening and a heart failure trial that looked at getting patients on “high intensity” treatment.
Find out the results here.

Show notes

Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial
Lancet 2022 Oct 22;400(10361):1417-1425

Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial

Lancet 2022 Dec 3;400(10367):1938-1952

Episode 551: Statins in older adults – there is an answer!

In episode 551, James and Mike invite Danielle Perry back to the podcast to talk about the best available evidence for the use of statins in people 65 and over. As you’ll hear, we have lots of evidence so all you need to know is what it says. Then, you can have an evidence-based discussion with all your people in this age category. After that discussion, your patient can make a decision one way or another and that means both of you win and you don’t have to care what guidelines say about this topic. Check it out.

Show notes

Tools for Practice
Statins in Older Adults

CFPC Learn

PEIP conference Oct 20-21 2023

Episode 549: Triglyce-Ride that High?

In episode 549, James and Mike invite Blair MacDonald to the podcast for the first time and we talk about a topic that we haven’t really covered to-date. We discuss the evidence around what happens to the risk of pancreatitis when we use triglyceride-lowering medications (fibrates, statins, niacin, omega-3s) in patients with hypertriglyceridemia. Have a listen as the results may surprise you somewhat.

Show Notes

Tools for Practice

Triglyce-Ride that High?

CFPC Learn

PEIP conference Oct 20-21 2023

Episode 548: Do you really need to measure lipoprotein(a) or apolipoprotein B

In episode 548, James and Mike invite Betsy Thomas back to the podcast to talk about whether or not measuring lipoprotein(a) or apolipoprotein B improves cardiovascular risk prediction in a meaningful way over and above using standard risk factors. Many guidelines are now recommending we should do these measurements but is this an evidence-based recommendation? Give us 30 minutes of your time and you’ll know the answer.

Show Notes

Less is More Unless it’s Sleep or Toilet Paper: Non-traditional lipoproteins for cardiovascular risk
Tools for Practice

CFPC Learn

PEIP conference Oct 20-21 2023

Episode 547: COPD – are the patients in primary care like those in the trials?

In episode 547, James and Mike invite Jessica and Scott back again to talk about whether or not COPD patients seen in primary care are like the people studied in the large COPD trials. We talk about how to focus care on the people who are most likely to benefit from therapy. There are lots of important primary care tips in this one. Have a listen.

Show Notes

Risk and distribution of chronic obstructive pulmonary disease–related hospitalizations among primary care patients
Canadian Family Physician June 2023, 69 (6) 409-414

CFPC Learn
PEIP conference Oct 20-21 2023

Episode 546: Who provides chronic disease management?

Episode 546: Who provides chronic disease management?

In episode 546, James and Mike invite Jessica Kirkwood and Scott Garrison to talk about a new study they published looking at what proportion of common chronic medical conditions such as hypertension, diabetes and COPD are handled by family physicians, specialists, and nurse practitioners manage. We find that family physicians provide the majority of care for these conditions. Tune in to find out the actual numbers and possibly how these findings should be used.

Show Notes

Who provides chronic disease management?
Canadian Family Physician June 2023, 69 (6) e127-e133 

CFPC Learn

PEIP conference Oct 20-21 2023

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The 2024 MEME Conference – May 24-25, 2024

REGISTRATION COMING SOON

Making Evidence Matter For Everyone | May 24 & 25, 2024
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice

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BIG ANNOUNCEMENT

THE NUTRITION PROPOSITION BOOK

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

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