TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
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Episode 283: PREMIUM – Glucose, blood pressure and statin studies to the max

In episode 283, Mike and James discuss the latest T2DM study showing that sitagliptin at least doesn’t cause much harm. We then veer off to discuss everything you need to know about diastolic and systolic blood pressure and how are they associated with CVD. Finally we discuss an n-of-1 study looking at statin-related myalgia. Bottom line – this was clearly a PREMIUM podcast.

Show notes

1) TECOS – Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes

N Engl J Med 2015; 373:232-242

2) Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

Lancet 2014;383:1899-1911

3) N-of-1 (Single-Patient) Trials for Statin-Related Myalgia

Ann Intern Med 2014;160:301-310

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