In episode 341, James and Mike talk about the long awaited trial of evolocumab that evaluated the impact it has on cardiovascular outcomes. Certainly not a homerun – maybe a very expensive full swing bunt with an error that leads to a single.
Show notes
1) Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
2) mystudies.org
In episode 340, Mike and James get all bent out of shape when they discuss the evidence around spinal manipulative therapy and low back pain. The evidence suggests no reliable effect for acute pain but the possibility of an effect for chronic pain. But any recommendations are a stretch because of the poor quality of the evidence.
Show notes
Tools for practice
Manipulating research for spinal manipulative therapy for low back pain
In episode 339, Mike and James talk about the evidence that has do with do with whether you need to use sterile gloves and saline for excisions and lacerations. The answer is that you should insert a suppository with the non-tapered end first. Listen to the podcast and see how we come to that conclusion.
Show notes
1) Tools for practice
All You Need is Glove: Are non-sterile gloves safe for excisions in the office?
Lacerations: Sterile Gloves & Water?
2) Rectal suppository: commonsense and mode of insertion
In episode 338, Tina, Mike and James go over the best available evidence around the treatment for recurrent vulvovaginal candidiasis and we find that we can reduce relapse with regular use of azole antifungals or we could just treat when symptoms occur – guess what, it’s all up to patient preference. Oh, and treating the partner makes no difference.
Show notes
Tools for Practice
In episode 337, Mike and James yet again go over even more studies that you really need to know about. We cover questions around duration of antibiotics for otitis media, NSAID cardiovascular safety and children with atopic dermatitis and the need for bathing before applying steroids. And the answers are yes, no and maybe, except on Tuesdays.
Show notes
1) Shortened Antimicrobial Treatment for Acute Otitis Media in Young Children
JAMA Intern Med 2016;176:1257-65
2) Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis
3) A randomized, controlled trial comparing topical steroid application to wet versus dry skin in children with atopic dermatitis
In episode 336, James and Mike finish their review of clinical practice guidelines. We talk about how well clinicians and patients understand the benefits and harms of treatments and tests and then end with how the perfect clinical practice guideline should be written.
Show notes
In episode 335, James and Mike continue their review of clinical practice guidelines. We discuss who writes the guidelines and if they mention values and preferences. At the end we let everyone know about the upcoming 28th annual BSM course on April 7/8, 2017 in Vancouver.
Show notes
In episode 334, Mike and James present the real evidence around a fictional, or is he, Santa Claus. We give everyone an evidence-based present wrapped in a systematic review. We discuss if Santa makes us kinder, and – SPOILER ALERT – when do children stop believing in Santa and does finding out scar them emotionally for life.
Show notes
Tools for Practice
In episode 333, James and Mike do a review of what we know about clinical practice guidelines. We discuss how guidelines are graded and what would make them awesome – and then reality sets in, quickly followed by depression.
Show notes
In episode 332, James and Mike put a finishing touch on their upstanding erectile dysfunction discussion. We spend most of the podcast talking about treatments and options for ED and at the end we decide to never again be in the same room when talking about such a sensitive topic.
Show notes
See previous podcast
THE NUTRITION PROPOSITION BOOK
Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.
This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)
