In episode 143, Mike and James quickly create headaches among their listeners but fortunately just as quickly get to a discussion about the prevention of headaches with antidepressants. We find out that tricyclics work but SSRIs don’t. To prove that point we both take high doses of fluoxetine during the podcast with no effect, except the clear effect it has on the quality of the podcast.
Tricyclics for preventing headaches
SSRIs for preventing headaches
Prophylaxis of migraine review