TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 609: Does exercise help pain or function in fibromyalgia?

In episode 609, Jamie and James chat with Jennifer Young about what the evidence says around exercise for fibromyalgia. Unfortunately, the evidence and the way it is presented is somewhat limited but nonetheless we do put it into context to help you and your patients make decisions.

Show Notes
1) Tools For Practice
Use the soft touch for buckle fractures?
https://cfpclearn.ca/tfp396/

2) PEIP Conference Edmonton October 17-18, 2025
https://www.peipconference.ca

Episode 608: Use the soft touch for buckle fractures?

In episode 608, Tina and James invite Jennifer Young back again to the podcast to go over the evidence we have for a simple but important question around buckle fractures – does treating with a soft bandage versus a rigid splint/cast produce different clinical outcomes? The answer is quite clear around what we should do. Check out what we found.

Show Notes
1) Tools For Practice
Use the soft touch for buckle fractures?

2) PEIP Conference Edmonton October 17-18, 2025

Episode 607: Trying Tongue-Tie Treatment: Does Frenotomy Fix Feeding Frustrations?

In episode 607, Tina and James invite Caitlin Finley to go over what the group found with regard to the best available evidence around surgical frenotomy. We look at the effect the surgery has on breast pain, self-reported breastfeeding improvement, and infant weight gain. Tune in as you might be impressed with the absolute benefits.

Show Notes
1) Tools For Practice
Trying Tongue-Tie Treatment: Does Frenotomy Fix Feeding Frustrations?

2) PEIP Conference Edmonton October 17-18, 2025

Episode 606: Avoiding the void? Mirabegron for overactive bladder

In episode 606, Jamie and James go over the best available evidence we have for the medications used in overactive bladder, with a focus on a newer agent mirabegron. We end up having to discuss the exciting topics of number of voids and dry mouth and at the end we give you all the numbers you need to have an evidence-based conversation with your patients.

Show Notes
1) Tools For Practice
Avoiding the void? Mirabegron for overactive bladder

2) PEIP Conference Edmonton October 17-18, 2025

Episode 605: An ASA a day keeps the Afib at bay?

In episode 605, James and Jamie get Emelie Braschi to answer a simple and common clinical question. ASA versus direct oral anticoagulants – which one is safer with regard to bleeding? As always it comes down to the numbers and we go over all those numbers and put them into the overall benefit and harm ratio for Afib.

Show Notes
1) Tools For Practice
An ASA a day keeps the Afib at bay?

2) SparcTool – Stroke Prevention in Atrial Fibrillation Risk Tool

3) PEIP Conference Edmonton October 17-18, 2025

 

Episode 603: Topical minoxidil for androgenetic alopecia: When blood pressure agents make you hairy

In episode 603, James and Mike K invite Jennifer Young back to the podcast to talk about the best available evidence for topical minoxidil and hair growth. We discuss outcomes such as the numbers of hairs per squared centimeter – the main outcome reported – but when available, we also other report on other outcomes and also the side effects. So, if you want to know about numbers of hair per squared centimeter and all the other numbers, tune in.

Show Notes
1) Tools For Practice
Topical minoxidil for androgenetic alopecia: When blood pressure agents make you hairy
2) PEIP Conference Edmonton October 17-18, 2025

Episode 602: Side effects of long-term PPI use: Leaving a bad taste in your mouth?

In episode 602, James and Mike Kolber go over the best available evidence for the benefits and the harms for one of the most commonly used classes of medications – proton pump inhibitors. We find out the benefit numbers are much larger than the harm numbers. Check out the podcast to get all the numbers you need to help people make decisions.

Show Notes
1) Tools For Practice
Side effects of long-term PPI use: Leaving a bad taste in your mouth?
Proton Pump Inhibitors (PPIs): Is Perpetual Prescribing Inevitable?

2) PEIP Conference Edmonton October 17-18, 2025

3) SPARCTool

4) RX files PPI
Stopping your Proton Pump Inhibitor or “PPI”

Episode 601: Gabapentinoids for fibromyalgia – do they ease the pain?

In episode 601, James and Mike invite Jennifer Young back to the podcast to go over all the evidence we have for pregabalin and gabapentin in patients with fibromyalgia. During the discussion we find out how many people actually get a ≥30% reduction in pain compared to placebo. We even look at some information about different doses. All the numbers are revealed by the end of the podcast – and we give tips and suggestions throughout. Check it out.

Show Notes
1) Tools For Practice
Pharm for Fibro, Round 2: Can gabapentinoids ease the pain?

2) MEME Conference 2025 in Vancouver – May 9/10, 2025

Episode 600: Exercise for Parkinson’s Disease: More movement = Better movement?

In episode 600, James and Mike invite Jamie Falk back to the podcast again and we talk about if exercise helps movement in Parkinson’s disease. You might be surprised by the size of the effect so have a listen and get all the evidence and numbers you need.

Show Notes
Tools For Practice
Exercise for Parkinson’s Disease: More movement = Better movement?

MEME Conference 2025 In Vancouver – May 9/10, 2025

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The 2026 MEME Conference – May 8-9, 2026

REGISTRATION IN JANUARY 2026

Making Evidence Matter For Everyone | May 8-9, 2026
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice

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BIG ANNOUNCEMENT

THE NUTRITION PROPOSITION BOOK

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

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