Episode 233: A passing podcast for the failing heart – PART II
In episode 233, Mike and James continue on with how to deal with a failing heart. We talk about nitrates, digoxin and the aldosterone antagonists. We then talk about the approach to using these medications and how we don’t need to get to everybody to high doses of every drug and in fact that this causes considerable harm unless it is done carefully.
Show notes
1) Nitrates
2) DIG trial
3) Aldosterone antagonists
Tools For Practice
Aldosterone antagonists in systolic heart failure – no longer an afterthought
4) Target dose evidence
Network – ACE doses
ATLAS – ACE doses
Carvedilol doses
Beta-blocker doses
Ann Intern Med 2009;150:784-94
Getting to carvedilol doses
HEAAL – losartan
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