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Episode 232: A passing podcast for the failing heart

In episode 232, Mike and James get to all the evidence around drugs for heart failure. We talk about furosemide, ACE inhibitors, beta-blockers and ARBs. The bottom line is that we have good evidence for reduction in mortality and heart failure admissions however the evidence for symptomatic control is surprisingly absent and both our hearts fail a little bit because of that news. 

Show notes

1) Diuretics

Cochrane CD003838

2) ACE inhibitors

Lancet 2000;355:1575-81

3) Aldosterone antagonists in systolic heart failure – no longer an afterthought  

Tools For Practice 

4) Beta-blockers

Ann Intern Med 2001;134:550-60

5) ARBs

PLOS 1 2010

6) Carvedilol vs metoprolol

Lancet 2003;362:7-13

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