TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 69: More studies you need to know about

In episode 69, the “Two Mikes” are back at it and they use their mics to dispense some really great prescriptive advice for patients with asthma and no heart burn pain and backs and knees which do have pain. James sits back and goes along for the ride but develops back and knee pain by the end, and the Mikes recommend a full body CT scan.

Show Notes

1) In patients with uncontrolled asthma and no GERD, the use of a PPI does not improve asthma symptoms

N Engl J Med 2009;360:1487-99

2) The use of PPIs and other GERD treatment in patients with asthma and acid-reflux symptoms shows no benefit in asthma symptoms

Chest 2005;128:1128–35

Cochrane Review 2003, No.: CD001496

2) Lumbar imaging for low-back pain without indications of serious underlying conditions does not improve clinical outcomes

Lancet 2009;373:463–72

3) Incidental meniscal findings on MRI of the knee are common in the general population and increase with increasing age

N Engl J Med 2008;359:1108-15

4) Arthroscopic surgery for osteoarthritis of the knee – no benefit

N Engl J Med 2002;347:81-8

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