In episode 401, Mike and James continue to try to show they aren’t therapeutic nihilists. We talk about the ballpark benefits of treating conditions like diabetes, with a focus on nutrition and activity to reduce cardiovascular risk.
Show notes
In episode 400, Mike and James talk about why they think they aren’t therapeutic nihilists and what it means to be a healthy skeptic. We then have a much longer discussion (which will go into the next few episodes) about many of the treatments that really do work. In this podcast we talk about treatments for BP, A fib and heart failure.
Show notes
In episode 399, Mike and James discuss a new paper researched and written by the Alberta gang. There are many reasons why patients are seen in primary care. This systematic review gives all the data on what are globally, the most common presenting conditions in primary care.
Show notes
What are the most common conditions in primary care?
In episode 398, James and Mike continue their discussion of the evidence around the class of agents called monoclonal antibodies. In this podcast we focus on medications that have an effect on symptoms and at the end we put the entire class into perspective – at least as much as we can.
Show notes
In episode 397, James and Mike discuss the evidence around the class of medications called monoclonal antibodies. We talk a little bit about them as a whole and then talk specifically about 6 different agents and the trials that have looked at the effectiveness of these interesting new medications. We come to the conclusion that you need to treat these agents, just like any new medication, by looking at the best available evidence.
Show notes
In episode 396, Mike and James present PREMIUM information from a premium province (BC). We discuss new studies that looked at measurements of blood pressure and bone density. At the end we put all of this information into a premium perspective.
Show notes
Tools for Practice
1) Association of Repeated Measurements With Blood Pressure Control in Primary Care
JAMA Internal Medicine 2018;178:858-60
2) Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial
In episode 395, James and Mike bring in Adrienne to chew and digest all the evidence around the ketogenic diet. At the end we realize we will likely never have definitive evidence around these diet issues so we all commiserate by drowning our sorrows in a large helping of deep fried Mars Bars.
Show notes
Tools for Practice
Less Pancakes, More Bacon? The Ketogenic Diet for Weight Loss
In episode 394, James and Mike bring in Tina and Joey to look at all the evidence around omega-3 supplements and dry eye and, despite widespread use, the evidence is far from convincing.
Show notes
Tools for Practice
Omega-3 Supplements for Dry Eye: Fishy evidence or a big catch?
In episode 393, James and Mike bring in Tina to deal with the issue of the evidence around CPAP. We find out that there is little evidence that CPAP reduces CVD so it is all about does the person feel better while on it – over and above the nuisance and cost.
Show notes
Tools for Practice
In episode 392, James and Mike get back to work after a European tour and other reasons. We go over the results from the latest large aspirin trials and, low and behold, the results show pretty much what we already knew.
Show notes
1) Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Lancet 2018 Aug 24. pii: S0140-6736
2) Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus
N Engl J Med. 2018 Aug 26. doi: 10.1056/NEJMoa1804988
3) The best CVD risk calculator
THE NUTRITION PROPOSITION BOOK
Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.
This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)
