In episode 154, Mike and James discuss the whole issue of why we use antibiotics. We discuss patient preferences, the use of delayed antibiotics, diagnostic uncertainty and at the end of the podcast we realise that the whole thing is tricky and so we give tips and tricks for how to deal with all the confusion.
Show notes
In episode 153, James and Mike attempt to breath life into a new agent for COPD called roflumilast. Unfortunately, by the end of the podcast we find out that the effect of this agent doesn’t leave Mike and James breathless but unfortunately it will leave our COPD patients that way.
Show notes
1)Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease
2) Is roflumilast (Daxas®) beneficial as an add-on therapy in the management of COPD?
3) Tiotropium or salmeterol for COPD?
In episode 152, Mike and James stream to the listeners a synopsis of the literature associated with treatments for overactive bladder and urge incontinence. Despite constant interruptions by James, Mike is able to provide a torrent of useful tips and suggestions for this common problem.
Show notes
1) Diagnosing Incontinence
Ann Intern Med 2006;144:715-723
2) Anticholinergics and pelvic floor exercises
Ann Intern Med 2008; 148; 459-73
3) Overactive bladder, urge incontinence and anticholinergic drugs
4) Overactive bladder drugs
Cochrane 2006;4:CD00378
Cochrane 2007;4:CD003190
Cochrane 2005;3:CD005429
In episode 151, James and Mike start of the new year with premium information so, by law we had to put it in a PREMIUM podcast. The first study we looked at was AIM-HIGH which showed us that we might need to re-assess how we use niacin and we finally have some reasonable data that helps us figure out how long to stay on a bisphosphonate.
Show notes
1) AIM-HIGH – Niacin added to statins in patients with cardiovascular disease
N Engl J Med 2011; 365:2255-67
2) The idolatry of the surrogate
3) HORIZON-Pivotal Fracture Trial – using zoledronic acid for 3 years or 6 years
THE NUTRITION PROPOSITION BOOK
Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.
This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)
