In episode 225, James and the Mikes talk about vaccines for adults. In part one of this series, we discuss the effectiveness of the influenza vaccine, the benefit seen in the elderly and what happens when we vaccinate health care providers.  We find that the evidence is not bad, but it is not overwhelming either, and so at the end we all make different decisions as to what to do and we are all correct. You have to love informed decision making.

Show notes

 1) Tools for practice

Effectiveness of seasonal influenza vaccine for healthy, working age adults

Will the flu shot help my Grandma and Grandpa?

2) Vaccines for preventing influenza in the elderly

Cochrane – CD004876

JAMA 1994;272:1661-5

3) Vaccinating health care providers

Cochrane – CD005187

In episode 224, James and Mike talk generically about generic medications and come up with some generic recommendations for how to generically use generic medications. At the end of the podcast they brand their podcast as being excellent.

Show notes

1)  Backlash against bioequivalence

CMAJ 2011;183:1350-1

2) Bioequivalence

Ann Pharmacotherapy 2009;43:1583-97

3) Clinical comparisons

 JAMA 2008;300:2514-26

4) Generic deception trial

Journal of Generic Medicines 2005;2:201–8

In episode 223, Mike and James get back to being PREMIUM and briefly discuss 4 new studies that we think you might find interesting. These studies primarily back up a lot of what we have said in the past so we present this evidence with vigour and ignore the rest of the contradictory data – JUST kidding. 

Show notes

1) Pioglitazone

Diabet Med 2013;30:1026–32

cvdcalculator.com

2) Treatment of fever

J Pediatr 2013;163:822-827.e2

3) Bone density measurements

JAMA 2013;310:1256-62

4) Steroids for tennis elbow

JAMA 2013;309:461-9