In episode 357. Mike and James invite Adrienne to help us work through all the studies that have looked at using riboflavin to prevent migraines. Unfortunately, the impact of riboflavin on migraines is consistently inconsistent and most RCTs found no reduction in migraine frequency. At least we have evidence for low-dose propranolol and amitriptyline.

Show notes

Tools for Practice

Riboflavin for Migraine Prophylaxis: Something “2-B” excited about?

In episode 356, Mike and James welcome Jamal Ramji to the podcast because we really needed to do something PREMIUM. We discuss a study of subclinical hypothyroidism and a low FODMAP diet for IBS. At the end we figure out that TSH is a no, but that the low FODMAP is a yes at least for 1 in 5-10 people.

Show notes

1) Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism

N Engl J Med 2017;376:2534-4

2) A Randomized Controlled Trial Comparing the Low FODMAP Diet vs. Modified NICE Guidelines in US Adults with IBS-D

Am J Gastroenterol 2016;111:1824-32