In episode 479, Mike and James update the latest information around cannabinoids for chronic pain. Unfortunately, there is not a lot of new information but we talk about what there is and then try and put all the evidence into context and then how to think about the information we have.

Show notes

1) Allan GM, Finley CR, Ton J, Perry D, Ramji J, Crawford K, et al. Systematic review of systematic reviews for medical cannabinoids: Pain, nausea and vomiting, spasticity, and harms.

Can Fam Physician. 2018;64(2):e78-e94.

2) Mücke M, Phillips T, Radbruch L, Petzke F, Häuser W. Cannabis-based medicines for chronic neuropathic pain in adults.

Cochrane Database Syst Rev. 2018 Mar 7;3(3):CD012182.

3) Wong SSC, Chan WS, Cheung CW.  Analgesic Effects of Cannabinoids for Chronic Non-cancer Pain: a Systematic Review and Meta-Analysis with Meta-Regression.

J Neuroimmune Pharmacol. 2020 Dec;15(4):801-829

4) Johal H, Devji T, Chang Y, Simone J, Vannabouathong C, Bhandari M.  Cannabinoids in Chronic Non-Cancer Pain: A Systematic Review and Meta-Analysis.

Clin Med Insights Arthritis Musculoskelet Disord. 2020 Feb 19;13:1179544120906461.

5) Fitzcharles MA, Baerwald C, Ablin J, Häuser W. Efficacy, tolerability and safety of cannabinoids in chronic pain associated with rheumatic diseases (fibromyalgia syndrome, back pain, osteoarthritis, rheumatoid arthritis): a systematic review of randomized controlled trials.

Schmerz. 2016;30(1):47–61.

In episode 478, James and Mike invite Jen Potter to the podcast yet again to talk about whether or not NSAIDs are effective for reducing menstrual bleeding. While the quality of the evidence is not great, there does appear to be some evidence that NSAIDs have an effect over placebo.

Show notes

Tools for Practice

How to Slow the Flow: NSAIDs for Heavy Menstrual Bleeding

In episode 477, James and Mike invite Jen Potter to the podcast for the first time to talk about the important topic of what to do around vaccine hesitancy. We find out the evidence suggests discussion should focus on the disease-prevention benefits for the individual rather than talking about misinformation around the harm or the benefits to society.

Show notes

Tools for Practice

Vaccine hesitancy in the office: What can I do?