Episode 163: How to analyse a meta-analysis and at the end not need analysis – PART II
In episode 163, Mike and James race to the end of their in-depth look at critical appraisal and as they get to the end their final kick is at some of the problems seen with meta-analyses. We discuss examples of how meta-analyses sometime go wrong and we do our best to make them right – with varying degrees of success.
Show notes
1) Glucose lowering meta-analysis
Ann Intern Med 2009;151:394-403
2) Beta-blocker meta-analysis
3) PSA screening
BMJ 2010;341:c4543 doi:10.1136/bmj.c4543
3) Statin meta-analyses on mortality effect in primary prevention
RR 0.88 (0.81-0.96)
Arch Intern Med 2010;170:1024-31
RR 0.91 (0.83-1.01)
Arch Intern Med 2005;165:725-30
RR 0.86 (0.76 -0.99)
Arch Intern Med 2006;166:2307-13
RR 0.92 (0.84-1.01)
J Am Coll Cardiol 2008;52:1769-81
RR 0.93 (0.87-0.99)
4) Back pain meta-analysis
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