In episode 571, James and Mike talk about 2 new papers – we learn what antibiotics we can use for community-acquired pneumonia and we also talk about the prevalence and management of dyslipidemia in Canadian primary care practices and find out who has this problem and who gets treated.

Show Notes
Identifying the Best Initial Oral Antibiotics for Adults with Community‐Acquired Pneumonia: A Network Meta‐Analysis
J Gen Intern Med. 2024 Feb 15.doi: 10.1007/s11606-024-08674-1.

Prevalence and management of dyslipidemia in primary care practices in Canada
Can Fam Physician. 2024 Mar;70(3):187-196.doi: 10.46747/cfp.7003187

In episode 570, James and Mike finish their trilogy on statistics. We take what we discussed in the previous podcasts and go through a couple of examples that will hopefully solidify what all the terms and numbers really mean.

Show Notes
1) Sensible Medicine
Doing statistics can be difficult but understanding them can be fairly simple
2) Analysis of 567,758 randomized controlled trials published over 30 years reveals trends in phrases used to discuss results that do not reach statistical significance
PLoS Biol 2022: e3001562. https:// doi.org/10.1371/journal.pbio.3001562

In episode 569, James and Mike continue to go over what statistics really show – we focus on what inferential statistics can and cannot do, what a p value means and more importantly what it doesn’t mean. And yes we try to keep all this stat stuff on a realistic and practical level – easier said than done.

Show Notes
Sensible Medicine
Doing statistics can be difficult but understanding them can be fairly simple

In episode 568, James and Mike go over what statistics really show – and importantly what they don’t show. We go over the terms and nuances and hopefully put them all into a simple context. Statistics are not just in medicine – they are in much of what you do every day – so you really do need to understand them.

Show Notes
Sensible Medicine
Doing statistics can be difficult but understanding them can be fairly simple

In episode 567, Mike and James revisit the old topic of industry influence on health care providers. We go over the issues, the nuances and some of the latest evidence around the interactions, the influence, and patient perceptions.

Show Notes

1) Industry Evidence Handout

2) MAKING EVIDENCE MATTER for EVERYONE CONFERENCE
Vancouver
May 24/25, 2024

Home

In episode 566, Mike and James invite Émélie back yet again to the podcast and the topic is the balance of benefits to harms of using corticosteroids in adults or children for atopic dermatitis. We come to the realization, as always, that how to use topical corticosteroids is based on knowing the best available evidence and then using lots of common sense – we give you all of that in just 30 minutes.

Show notes

Tools for Practice
Topical corticosteroids for atopic dermatitis – More than skin deep

MAKING EVIDENCE MATTER for EVERYONE CONFERENCE
Vancouver
May 24/25, 2024

In episode 565, Mike and James invite Émélie Braschi back to the podcast to talk about do-it-yourself hearing aids. We find some very interesting information about how direct-to-consumer self-fitted hearing aids compare to conventional hearing aids fitted via audiogram. You really need to listen to this podcast – your patients will thank you.

Show notes

Tools For practice

Do-It-Yourself Hearing Aids

MAKING EVIDENCE MATTER for EVERYONE CONFERENCE
Vancouver
May 24/25, 2024

Episode 564: Can non-hormonal drugs improve vasomotor symptoms in menopause?

In episode 564, Mike and James invite Samantha Moe back to the podcast to talk about the benefits and harms of non-hormonal medications for vasomotor symptoms in menopause. We find they do have an effect over placebo but also people in the placebo group improve, so you need to know all the numbers. We give you those and so much more so please spend 28 minutes with us when you get a chance.

Show notes

Tools For Practice
Turn Down the Heat! Can non-hormonal drugs improve vasomotor symptoms in menopause?
MAKING EVIDENCE MATTER for EVERYONE CONFERENCE
Vancouver
May 24/25, 2024

In episode 563, Mike and James go over all the RCT evidence for the Respiratory Syncytial Virus (RSV) vaccine in older adults. You need to know the vaccine works, but you really need to know the baseline risk of RSV before anyone can really make an informed decision about this vaccine. We’ll do our best to give you all the numbers.

Show notes
Preventing RSV in the elderly

MAKING EVIDENCE MATTER for EVERYONE CONFERENCE
Vancouver
May 24/25, 2024

In episode 562, Mike and James continue to discuss our recently revised 2023 simplified lipid guidelines with Adrienne and Mike. We talk about all the medications used for cardiovascular risk reduction. We go over all the evidence and all the numbers for the benefits (and sometimes lack of benefit) and the harms. We also specifically talk about how to deal with statin intolerance.

Show notes

1) PEER simplified lipid guideline 2023 update
2) Lipid-lowering therapies for cardiovascular disease prevention and management in primary care – PEER umbrella systematic review of systematic reviews
3) Simplified Cardiovascular Decision Aid