TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 513: To Pee or Not to Pee: Combination agents for benign prostatic hypertrophy

In episode 513, James and Mike invite Emelie Braschi to the podcast for the first time. We go over the best available evidence around the treatment of BPH and focus on the combination therapy of alpha-blockers and 5-alpha reductase and find as for many things there is an improvement in symptoms but also an increase in side effects.

Show Notes

Tools For Practice

To Pee or Not to Pee: Combination agents for benign prostatic hypertrophy

Episode 512: Alcohol, the cause of, and solution to, all of life’s problems – PART II

In episode 512, James and Mike finish going over the best available evidence around drinking alcohol. We look at what evidence says about the “red-wine” theory and the French Paradox. We also look at the evidence around alcohol and surrogate markers, and atrial fibrillation. We also examine the effect of social drinking on emotion and alcohol-induced cirrhosis.

Show Notes

Check out the book “The Nutrition Proposition” for all the references discussed. The book is available on Amazon as a paperback and a Kindle Edition

Website

Amazon link

Episode 511: Alcohol, the cause of, and solution to, all of life’s problems

In episode 511, James and Mike go on a binge and dissect the best available evidence around alcohol – more specifically 0-3 drinks a day. We look at what is a “drink” and then dive into one of the largest reviews of alcohol ever done. We explore what that evidence suggests about the harms and the benefits, and as always we discuss what the numbers really say.

Show Notes

Check out the book “The Nutrition Proposition” for all the references discussed. The book is available on Amazon as a paperback and a Kindle Edition

  1. Website
    nutritionproposition.com
  2. Amazon link

Episode 510: PREMIUM – Stopping antidepressants, and starting ASA in pregnancy

In episode 510, Mike and James talk about a trial that looks at what happens when you discontinue antidepressants in primary care. We see there is about a 15% absolute difference in the chance of relapse – and we put all this into context because this is a PREMIUM podcast. We also discuss what happens…

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Episode 509: Removing the pain from dealing with chronic pain – PART IV

In episode 509, James, Mike and Tina finish talking about our new clinical practice guideline on chronic pain. We focus on the top questions we all have in chronic pain and also discuss the best available evidence for the many different medications we use for chronic pain.

Show Notes

  1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
  2. Guideline summary
  3. Patient Handout
  4. PEER pain calculator
  5. Tame the Beast

 

Episode 508: Removing the pain from dealing with chronic pain – PART III

In episode 508, James and Mike ask Tina to come in and talk about our new clinical practice guideline on chronic pain. We focus on the best available evidence which shows that physical activity is key (except for neuropathic pain). We also go over the role for psychological interventions and the problem with opioids.

Show Notes

  1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
  2. Guideline summary
  3. Patient Handout
  4. PEER pain calculator

Episode 506: Removing the pain from dealing with chronic pain

In episode 506, James and Mike invite Adrienne Lindblad to discuss our latest clinical practice guideline on the management of chronic low back, osteoarthritic, and neuropathic pain in primary care. In this episode we describe the development process and then highlight the best available evidence, including both benefits and harms, for chronic osteoarthritis treatments. We talk about the other chronic pain topics in episode 507 so keep listening.

Show Notes

  1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
  2. PEER pain calculator

 

Episode 505: NephMadness 2022 – albuminuria, basketball and the Great White North

In episode 505, James and Mike invite nephrologists Samira Farouk and Matthew Sparks to discuss the tricky issue of albuminuria – who to monitor, what to monitor and who to treat. We spend a lot of time dribbling and end up deciding that nothing is a slam dunk, so stay until the end for a real buzzer beater.

Show Notes

1) ACR variability

AJKD 2013;62:1095–1101

2) Kidney Failure Risk Equation

3) Albumin Handout

4) American Journal of Kidney Disease Blog

5) NephMadness 

6) May 27/28. 2022 The MEME conference – Making Evidence Matter For Everyone

Episode 504: Can It Stay or Must It Go? Extended Use of Intrauterine Devices

In episode 504, James and Mike invite Jen Potter back to the podcast to talk about whether or not intrauterine devices for preventing pregnancy can be used beyond the recommended duration of use. It seems one can defer IUD replacement for at least up to 12 months. Have a listen and see what you think.

Show Notes

1) Tools for Practice
Can It Stay or Must It Go? Extended Use of Intrauterine Devices

2) The Aural Apothecary Podcast – check it out

3) The MEME Conference – Make Evidence Matter for Everyone

4) CFPC Learn – Continuing Professional Development made by and for family physicians

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BIG ANNOUNCEMENTS

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

THE MEME CONFERENCE – Making Evidence Matter For Everyone

May 27-28, 2022 in Vancouver, BC

Our annual primary care evidence-based conference is BACK. The MEME conference is happening May 27/28 live and virtual in beautiful Vancouver, BC. Sure hope you can join us.

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BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

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