In episode 505, James and Mike invite nephrologists Samira Farouk and Matthew Sparks to discuss the tricky issue of albuminuria – who to monitor, what to monitor and who to treat. We spend a lot of time dribbling and end up deciding that nothing is a slam dunk, so stay until the end for a real buzzer beater.

Show Notes

1) ACR variability

AJKD 2013;62:1095–1101

2) Kidney Failure Risk Equation

3) Albumin Handout

4) American Journal of Kidney Disease Blog

5) NephMadness 

6) May 27/28. 2022 The MEME conference – Making Evidence Matter For Everyone

In episode 504, James and Mike invite Jen Potter back to the podcast to talk about whether or not intrauterine devices for preventing pregnancy can be used beyond the recommended duration of use. It seems one can defer IUD replacement for at least up to 12 months. Have a listen and see what you think.

Show Notes

1) Tools for Practice
Can It Stay or Must It Go? Extended Use of Intrauterine Devices

2) The Aural Apothecary Podcast – check it out

3) The MEME Conference – Make Evidence Matter for Everyone

4) CFPC Learn – Continuing Professional Development made by and for family physicians

In episode 503, James and Mike explore the evidence around water for a variety of different health outcomes. How much do we need and does it matter where we get it from? The only thing we know is that 8 glasses a day is wrong.

Show Notes

Coming soon

In episode 502, James, Mike Kolber and Tony Nickonchuk get together to talk about the easy question (just kidding) of COVID vaccines for children and adolescents. We discuss the best evidence we could find around efficacy and adverse effects in these age groups and hopefully give enough context so that you go from murky to somewhat less cloudy as to what we know and don’t know about this topic.

Show Notes

1) Tools for Practice
CO-KID: Covid vaccine for kids

2) Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents
January 12, 2022 DOI: 10.1056/NEJMoa2117995

3) Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12–18 Years — United States, June–September 2021

4) Effectiveness of BNT162b2 (Pfizer-BioNTech) mRNA Vaccination Against Multisystem Inflammatory Syndrome in Children Among Persons Aged 12–18 Years — United States, July–December 2021

James and Mike celebrate their 500th, YIKES, podcast episode. You get to hear the entire intro song (Some People) written and recorded by Pete McCormack. We talk about the history of the podcast, thank a lot of people, and talk about the key messages and the philosophy we have tried to impart over the years. We then discuss a few cases that bring all these ideas into focus. THANKS SO MUCH FOR LISTENING and going on this journey with us. We have had a blast.

Show Notes

Pete McCormack’s Website
Tools for Practice
PEER Evidence

In episode 499, James and Mike invite Tina back again to discuss the evidence we have for dieting to lose weight and the impact of that on osteoarthritis knee pain. Overall, there isn’t a lot of evidence but some observational data suggests a benefit Unfortunately the relatively small weight loss achieved from most diets in RCTs did not demonstrate a difference on OA pain.

Show Notes

Tools for Practice
No Gain, No Pain? – What is the effect of diet-induced weight loss on osteoarthritis-related knee pain?

In episode 498, James and Mike invite Tina back yet again to talk about all the evidence we have for using compression stockings in patients with chronic lower limb edema. The NNT for recurrent cellulitis is pretty good (listen to find out the actual number) on the “NNT scale”.

Show Notes

Tools for Practice
Under Pressure: Compression stockings for recurrent cellulitis?

In episode 497, James and Mike decide to go all in on the evidence around nutrition. We start out by going over how we try to actually figure out if a food is beneficial or harmful for you. And for nutrition is it ever tricky.

Show Notes

The Nutrition Proposition – Coming Soon – I hope

In episode 496, Mike and James continue the discussion with Ricky around the best available evidence we have for heart failure patients with preserved ejection fraction. Unfortunately, not much works but at least you’ll know the evidence. 

Show Notes

In episode 495, Mike and James invite Ricky back again to talk about the options (not a lot) we have for heart failure patients with preserved ejection fraction. Ricky goes over all the trials and helps put them into context.

Show Notes