Episode 11: Taking the Pressure off: Other Drugs
In our 11th episode, we discuss the laundry list of the remaining hypertensive medications and their evidence. The issue of blood pressure as a surrogate marker is discussed and we encourage clinicians to focus on hypertensive agents that effect patient oriented outcomes. While the evidence is reasonable for Ca+ Blocker, we put Beta-blockers low down (and Atenolol off) the list with Alpha-blockers and a few others.We have few laughs along the way, primarily at our lack of humor.
Show Notes
1) Atenolol no better than placebo and other drugs are better than atenolol in reducing cardiovascular outcomes in patents with high blood pressure
2) Beta-blockers do appear to increase the chance of developing diabetes
3) A debate on using or not using betablockers for high blood pressure
Can Fam Physician 2007;53:614-7
4) ALLHAT – the problem with alpha-blockers
5) Data for felodipine and cardiovascular events in patients with high blood pressure
6) Use of low-dose spironolactone in “resistant” hypertension
7) Effect of spironolactone on albuminuria
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