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Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 266: Questions, questions, questions PART IV

In episode 266, James and Mike finally get to the end of listener questions. We talk about NSAIDs and inflammation, cognitive impairment and statins, dosing of antibiotics, antidepressants and efficacy, and antiplatelets and ethnicity. We give answers which either clarify or confuse the issues.

Show notes

1) Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis

Lancet 2009;373:746-58

2) Selective publication of antidepressant trials and its influence on apparent efficacy

N Engl J Med 2008;358:252-60

3) Why olanzapine beats risperidone, risperidone beats quetiapine, and quetiapine beats olanzapine: an exploratory analysis of head-to-head comparison studies of second-generation antipsychotics

Am J Psychiatry 2006;163:185-94

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The 2026 MEME Conference – May 8-9, 2026

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