Episode 422: PREMIUM – Statins do don’t not not work in older people – or do/don’t they?
In episode 422, James and Mike, go MEGA-PREMIUM and discuss the most recent meta-analysis (yes, yet another one) around the use of statins in older people. We then quickly review an article that looks at whether or not the guidelines for monitoring chronic conditions in primary care are evidence based. We are “shocked” when we find out “There is no evidence to support frequency of testing of any test in any of the guidelines”.
1) Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
Lancet. 2019 Feb 2;393(10170):407-415. doi: 10.1016/S0140-6736(18)31942-1
2) Are guidelines for monitoring chronic disease in primary care evidence based?
BMJ. 2019 Jun 13;365:l2319. doi: 10.1136/bmj.l2319
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