TEC: Evidence Based Therapeutics
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Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 51: More useful clinical trials – with a gentler touch – Part II

In episode 51, we again bring in the charming Dr. Tina Korownyk to help us work through 4 more recent studies that hopefully will have relevance to your practice. We find out that Vitamin B12 works for apthous ulcers, inhaled corticosteroids should be continued in pregnancy, that NSAID risks can be reduced – but not to zero, and an ARB (telmisartan) provides no benefit when given to stroke patients. Finally, it is revealed that Mike and James have very limited absolute charm.

Show Notes
1) Apthous ulcers – sublingual Vitamin B12

J Am Board Fam Med 2009;22:9 –16

2) GI protection for NSAIDs

Am J Gastroenterol  2009; 104:728-38

3) Asthma control in pregnancy – OK to use inhaled corticosteroids

Ann Allergy Asthma Immunol 2008;101:137–43

4) Telmisartan for stroke – no benefit

N Engl J Med 2008;359:1225-37

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