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Episode 54: CRP – An important part of a Comprehensive Risk Profile or a Completely Ridiculous Practice- Part III

Episode 54 finishes off the whole issue of CRP measurement by looking at the evidence we have about what happens to patients when they take drugs that lower CRP – glitazones, COX-2s, fibrates, vitamin E, niacin, ezetimibe, and statins. Other than statins and maybe niacin, it doesn’t look good – in contrast to Mike and James of course that is.

Show Notes

1) Drugs that lower CRP

Cardiovasc Drug Rev 2006;24:33-50

Chest 2004;125:1610-5

Atherosclerosis 2005;179:361-7

2)Drugs that lower CRP and their effect on outcome

Glitazones

JAMA 2007;298:1189-95

COX-2s

CMAJ 2002;166:1649-50

Fenofibrate

Lancet 2005;366;1849-61

Bezafibrate

Circulation 2000;102:21-7

Vitamin E

Lancet 2003;361:2017-23

JAMA 2007;297:842-57

Niacin

JAMA 1975;231:360-81

Ezetimibe

N Engl J Med 2008;358:1431-43

Statins

Lancet 2008;371:117-25

High dose statins – not treating to target

CMAJ2008;178(5):576-84

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11th Annual PEIP Conference October 21-22, 2022

Practical Evidence for Informed Practice Conference | October 21 & 22, 2022
Led by the team that brings you Tools for Practice, the Practical Evidence for
Informed Practice (PEIP) Conference brings together clinical leaders to speak on
the latest findings that can affect how you practice.

www.peipconference.ca

BIG ANNOUNCEMENTS

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

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BedMed: The High Blood Pressure Study

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