Episode 58: Type 2 Diabetes – how sweet it isn’t – Part IV
In episode 58, the fourth in our installment of podcasts on diabetes, we briefly talk about the evidence surrounding intensive glucose lowering (ACCORD, ADVANCE, VADT and UKPDS trials) – podcasts #9 and #38 did this in more detail. At the end of the podcast, Mike identifies many of James’ flaws, but does it with compassion and kindness; at least he says he does.
1) Does tight glycemic control burden patients with complex treatment programs, hypoglycemia, weight gain, and costs and offers uncertain benefits in return?
2) ACCORD and ADVANCE studies
Click here for a synopsis of the results
N Engl J Med 2008 358:2545-2559
N Engl J Med 2008 358:2560-2572
Also listen to Episode 9: News Flash: Aggressive Blood Sugar Control Not All Sweet
3) VADT trial N Engl J Med 2009;360:129-39
Also listen to Episode 38: New trials you need to know about
4) Glucose lowering meta-analysis – do the results support the conclusions?
5) UKPDS data
6)UKPDS – 10 year update (recent results)
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