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Episode 72: WE’RE BACK with Vitamin D, vim, and vigor

In episode 72, we find out what Mike has really been doing for the last 3 months by testing his Vitamin D level and finding it to be abnormally high. This leads us, along with our always charming guest Dr. Tina Korownyk, to a discussion of the proper use of Vitamin D levels and what they really mean. At the end of the podcast James and Mike both agree to do podcasts more often than every three months.

Show notes

1) Different reference Vitamin D levels

BC  Biomedical Labs

The Vitamin D Society

2) “the most-ordered hormone assay in the United States”

J Clin Endocrinol Metab 2009;94:1092–3

3) Vitamin D levels


CMAJ 2002;166(12):1517-24

Average levels

Am J Clin Nutr 2008;88:558S-564s

4) Multiple health outcomes and Vitamin D levels – nonvertebral fractures, hip fractures, periodontal disease, balance, colon cancer, falls

Am J Clin Nutr 2006;84:18–28

BMJ 2009;339:b3692

Arch Intern Med 2009;169:551-61

JAMA 2005;293:2257-2264

“whether an individual is found to have low or normal vitamin D status is a function of the laboratory used”

J Clin Endocrin Metab 2004;89:3152-7

5) Variability Differences between the mean values of labs was 38%

Ost Int 1999;9:394-7

Mean relative uncertainties between labs were 19.4%, 16.0%, and 11.3%

Ost Int 2009 – 9 September 2009 –Online

Within patient variability – 15-20%

Ost Int 1998 8:222–30

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