In episode 476, James and Mike talk about a few new systematic reviews from the Cochrane library that look at 4 different common antibiotic questions in primary care – antibiotics for secondary prevention of cardiovascular disease, molar tooth extraction, Strep throat, and COPD exacerbation prevention. The PREMIUIM answers are no, yes, yes and yes – but you need to know the details, so have a listen.

Show notes

COCHRANE REVIEWS

Antibiotics for secondary prevention of coronary heart disease

Antibiotics to prevent complications following tooth extractions

Different antibiotic treatments for group A streptococcal pharyngitis

Prophylactic antibiotics for adults with chronic obstructive pulmonary disease: a network meta‐analysis

In episode 475, Mike and James invite Tina to talk about treatments for restless legs syndrome. in particular pramipexole. We find that pramipexole improves symptoms in ~20% of people over and above placebo and that low doses are just as good as higher doses. Who knew? In addition, you need to know that over a long period of time (> 1 year) that pramipexole can worsen restless syndrome so reassessment on a regular basis is key.

Show notes

1) Tools for Practice

A good sleep would be dop(aminergic) doc! Pramipexole in restless legs syndrome

2) CFPCLearn – Interactive e-learning. Reporting Simplified anytime, anywhere

In episode 474, Mike and James discuss the evidence around intermittent iron dosing for people with anemia. We find that once daily dosing of iron yields similar or slightly better hemoglobin versus twice weekly or alternate day over ~3 months but low dose is still the place to start. We also discuss the amount of iron in supplements and in food and try to put all that into context.

Show notes

1) Tools for Practice

Iron dosing frequency: Is less more or just less?

2) CFPCLearn – Interactive e-learning. Reporting Simplified anytime, anywhere