TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 406: How well is opioid agonist therapy managed in primary care?

In episode 406, Mike, James, and Tina go over the evidence for treating opioid use disorder in primary care and the evidence is clear that it can be done in primary care but specialized opioid treatment programs are also obviously needed.

Show notes

1) Tools for Practice

Location, Location, Location: Treating patients with opioid use disorder in primary care

2) CFPC webinar – 12:00PM EST Feb 12, 2019

Top 10 take-home points for advance care planning in primary care

YouTube link: www.youtube.com/watch?v=-mWsMA39YOw

Episode 405: Buprenorphine-naloxone for pharmaceutical opioid use disorder

In episode 405, Mike and James, with yet again the very smart and helpful Tina Korownyk, go over the evidence for buprenorphine-naloxone for pharmaceutical opioid use disorder. While the evidence is at moderate to high risk of bias the results are fairly impressive with NNTs of 3-5.

Show notes

Tools for Practice

Is buprenorphine (with or without naloxone) effective as maintenance therapy in pharmaceutical opioid use disorder?

Episode 404: Does your patient have an opioid use disorder?

In episode 404, Mike and James, with the very capable Tina Korownyk, go over the approach to what tools to use to help determine if a patient has an opioid use disorder (OUD). We talk about a simple tool called the Prescription Opioid Misuse Index (POMI), a 6-point questionnaire with strong predictive ability for OUD which seems to be a reasonable case-finding tool. 

Show notes

Tools for Practice

Does this patient taking prescription opioids have opioid use disorder?

Episode 403: Therapeutic nihilists – I doubt that – PART IV

In episode 403, Mike and James finally finish up their clear demonstration as to why they aren’t therapeutic nihilists.  We focus on system/ecological issues and specifically primary care – the bottom line is things aren’t as bad as they sometimes seem, but things could always be better – you heard it here first.

Show notes

Handout

CFPC National Webinar – Learn about the top 2018 research studies  – Jan 9, 2019 – 12:00 EST Web link

Episode 400: Therapeutic nihilists – I doubt that

In episode 400, Mike and James talk about why they think they aren’t therapeutic nihilists and what it means to be a healthy skeptic. We then have a much longer discussion (which will go into the next few episodes) about many of the treatments that really do work. In this podcast we talk about treatments for BP, A fib and heart failure. 

Show notes

Handout

Episode 397: Monoclonal antibodies – trying to put these agents into context

In episode 397, James and Mike discuss the evidence around the class of medications called monoclonal antibodies. We talk a little bit about them as a whole and then talk specifically about 6 different agents and the trials that have looked at the effectiveness of these interesting new medications. We come to the conclusion that you need to treat these agents, just like any new medication, by looking at the best available evidence.

Show notes

Handout for MABs

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