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Episode 391: PREMIUM – 3 studies that will leave you short of breath

In episode 391, Mike and James have yet again a PREMIUM moment that will leave you short of breath. We go over 2 new studies that looked at asthma action plans and does increasing doses of inhaled corticosteroids work. In the last study we go over a comparison of vaginal estradiol, vaginal moisturizer or placebo for perimenopausal vulvovaginal symptoms, and placebo ends up working as well as anything else.

Show notes

1) Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations

N Engl J Med 2018;378:891-901

2) Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations

N Engl J Med 2018;378:902-910

3) Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms

JAMA Intern Med. doi:10.1001/jamainternmed.2018.0116

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