In episode 375, Mike and James continue getting high on the evidence around medical cannabinoids. We talk about the adverse effects associated with medical cannabinoids and find out it is fairly impressive in not only the number of patients who get them but also the different kinds of side effects.
Show notes
Systematic review of systematic reviews for medical cannabinoids
In episode 374, Mike and James get high by delving into a systematic review of medical cannabinoids. We put a flame to the evidence, munch on all the data and get the giggles around what the evidence actually shows. The bottom line is, there is evidence for its use in pain, nausea and vomiting, and spasticity but the evidence is at best stoned.
Show notes
Systematic review of systematic reviews for medical cannabinoids
In episode 373, Mike and James get back to the last of the listener questions. We talk about vaginal infections, statins (of course), diabetes, medical education, alcohol hand sanitizers and TPA yet again. As always, we leave everyone with more questions than before we started – you have to love healthcare.
In episode 372, James and Mike get back to even more listener questions. We talk about lipids, CBC screening, NNTs for lots of treatments, spinal manipulation and other medical podcasts. Yet again we hopefully leave the audience with more answers than questions.
Show notes
Tools for Practice
Manipulating Research for Spinal Manipulative Therapy for Low Back Pain
In episode 371, James and Mike get back to listener question. We talk about iron, TPA, big blood pressure numbers, antipsychotics and lab measurements. Hopefully we leave the audience with more answers than questions.
Show notes
1) Are we giving too much iron? Low-dose iron therapy is effective in octogenarians
2) Clot – dissolving drugs for treating ischaemic stroke in the early stages
3) Effect of Propranolol In Mild Hypertension
4) Head-to-head comparisons of metabolic side effects of second-generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis
In episode 370, Mike and James decide to follow their New Year’s resolution by trying to present some new studies in a useful and thoughtful way – in other words, a PREMIUM podcast. We talk about a trial of pregabalin for sciata, a trial of intra-articular steroid injections for knee pain, romosozumab/alendronate for fractures and antibiotics for small abscesses.
Show notes
1) Trial of Pregabalin for Acute and Chronic Sciatica
2) Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial
3) Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
N Engl J Med 2017; 377:1417-27
4) A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses
In episode 369, James and Mike ask Tina back again to talk about the tricky and tasty issue of peanut allergies. We talk about the landmark study in this area and then put it into context of all the other evidence we have around this issue. We then discuss what we should likely be recommending when it comes to peanut ingestion in early childhood.
Show notes
1) Tools For Practice
Early Peanuts for Little Peanuts: The not so paltry benefits
In episode 368, James and Mike ask Tina to talk about the evidence around sleep training for infant sleep issues. We find out that a simple training method implemented at around six months can have useful benefits for not only the infant but also the parent. Check it out.
Show notes
Tools For Practice
In episode 367, Mike and James talk about the latest cardiovascular medication canakinumab, and a systematic review of corticosteroids for the treatment of a sore throat. And to really make it PREMIUM we throw in a quick discussion about a new study on the T2DM medication exenatide.
Show notes
1) Antiinflammatory therapy with canakinumab for atherosclerotic disease
2) Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials
BMJ 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887
3) Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes
In episode 366, Mike, James, and Tony continue to talk about the very important and broad topic of social determinants of health. Interestingly, evidence is fairly clear that social spending may be more useful to health than health spending and we need more focus on community services and primary care.
Show notes
THE NUTRITION PROPOSITION BOOK
Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.
This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)
