In episode 335, James and Mike continue their review of clinical practice guidelines. We discuss who writes the guidelines and if they mention values and preferences. At the end we let everyone know about the upcoming 28th annual BSM course on April 7/8, 2017 in Vancouver.
Show notes
In episode 334, Mike and James present the real evidence around a fictional, or is he, Santa Claus. We give everyone an evidence-based present wrapped in a systematic review. We discuss if Santa makes us kinder, and – SPOILER ALERT – when do children stop believing in Santa and does finding out scar them emotionally for life.
Show notes
Tools for Practice
In episode 333, James and Mike do a review of what we know about clinical practice guidelines. We discuss how guidelines are graded and what would make them awesome – and then reality sets in, quickly followed by depression.
Show notes
In episode 332, James and Mike put a finishing touch on their upstanding erectile dysfunction discussion. We spend most of the podcast talking about treatments and options for ED and at the end we decide to never again be in the same room when talking about such a sensitive topic.
Show notes
See previous podcast
In episode 331, James and Mike talk about the ups and downs of erectile dysfunction. We take a penetrating look at the epidemiology and what initial assessments should be done – treatments will pop-up in the next podcast. Fortunately or unfortunately, we rarely raise our comments above what would be expected from 14 year-old boys.
Show notes
In episode 330, Mike and James do a PREMIUM job of looking at 2 important new publications about medications for type 2 diabetes. We look at an RCT of semaglutide that actually shows a benefit. We then look at a very thorough systematic review/meta-analysis of all the studies and publications around T2DM since 1998. The results demonstrate very clearly that the evidence doesn’t really support what is being written in the diabetes clinical practice guidelines.
Show notes
1) SUSTAIN-6
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
N Engl J Med 2016; 375:1834-44
2) Glycemic Control for Patients With Type 2 Diabetes Mellitus Our Evolving Faith in the Face of Evidence
Circ Cardiovasc Qual Outcomes. 2016;9:00-00. DOI: 10.1161/CIRCOUTCOMES.116.002901.
In episode 329, Mike and James continue with their update on the treatment of dementia. We talk about prevention and how to figure out if an individual is getting a benefit from treatment. Bottom line, it is very tricky. We also talk about non-drug treatments and the latest new drug treatment.
Show notes
See Episode 328
In episode 328, Mike and James do an update of what is new for the treatment of dementia. We go over the scales used to assess dementia and then look at the latest trials for the commonly used drugs. Sadly, the treatments are still sorely limited.
Show notes
In episode 327, Mike and James do a delicious podcast around the evidence for chocolate. We look at the cohorts and the RCTs that have looked at the effect of this heavenly food on outcomes like mortality, cardiovascular disease, blood pressure, depression and acne. The results make us happy and smile.
Show notes
In episode 326, Mike (with James just there for his charm) goes over three studies in the area of renal stones, testosterone, and sleep apnea and the outcome, as expected, can be considered nothing but PREMIUM.
Show notes
1) Medical expulsive therapy in adults with ureteric colic: a multicentre, randomised, placebo-controlled trial
2) Effects of Testosterone Treatment in Older Men
3) CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea
4) Laughing alongside the best of evidence: Family physicians change ideas about tools, knowledge, practice, and medicine
THE NUTRITION PROPOSITION BOOK
Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.
This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)
