TEC: Evidence Based Therapeutics
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Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 330: PREMIUM – Diabetes, all the good, the bad and the ugly

In episode 330, Mike and James do a PREMIUM job of looking at 2 important new publications about medications for type 2 diabetes. We look at an RCT of semaglutide that actually shows a benefit. We then look at a very thorough systematic review/meta-analysis of all the studies and publications around T2DM since 1998. The results demonstrate very clearly that the evidence doesn’t really support what is being written in the diabetes clinical practice guidelines.

Show notes

1) SUSTAIN-6 

Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

N Engl J Med 2016; 375:1834-44

2) Glycemic Control for Patients With Type 2 Diabetes Mellitus Our Evolving Faith in the Face of Evidence

Circ Cardiovasc Qual Outcomes. 2016;9:00-00. DOI: 10.1161/CIRCOUTCOMES.116.002901. 

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BIG ANNOUNCEMENTS

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

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