TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 519: Oh Baby – Combined oral contraceptives during breastfeeding

In episode 519, Mike and James ask Jen Potter back to the podcast to talk about a common primary care question around oral contraceptives and breast feeding. We review the best available evidence which unfortunately we find out is not the highest quality. Nonetheless, we go over the numbers and then come up with useful, hopefully, suggestions for what to do around this issue.

Show Notes
Tools for Practice
Oh Baby: Combined oral contraceptives during breastfeeding

Episode 518: Avoiding lactose-containing products during acute pediatric diarrhea

In episode 518, Mike and James get Samantha to go through all the evidence we have for restricting lactose-containing foods in children with acute diarrhea. While we find out that looking at this evidence is at best tricky, it seems like reducing or diluting formula may provide a reasonable benefit. Listen to the podcast for the numbers.

Show Notes
Tools for Practice
“Not Milk?”: Avoiding lactose-containing products during acute pediatric diarrhea

Episode 516: The LARC (long-acting reversible contraception) Song: Is the etonogestrel implant a hit?

In episode 516, James and Mike invite Nicolas Dugré to the podcast yet again, and this time we talk about the evidence around the latest long-acting implantable reversible contraception. As always, we talk about the efficacy, the harm and all the rest of the issues around the use of these forms of contraception.

Show Notes

Tools For Practice
The LARC (long-acting reversible contraception) Song: Is the etonogestrel implant a hit?

Check out the Pharmascope Podcast – The French “version” of the BS Medicine Podcast

Episode 515: Weight to Go: Naltrexone/bupropion for weight loss

In episode 515, James and Mike invite Allison Paige to the podcast for the first time. Alli takes us through all the evidence around a combination product (naltrexone/bupropion) for weight loss. We talk about all the numbers we have for benefit, harm and cost and we put this agent into the context of the other medications we use for weight loss.

Show Notes

Tools For Practice

Weight to Go: Naltrexone/bupropion for weight loss

Episode 514: Antihistamines for allergic rhinosinusitis: ‘Achoo’sing the right treatment

In episode 514, James and Mike invite Betsy Thomas to the podcast for the first time. We look at a very common condition that many of us have at some point in our lives – allergic rhinosinusitis. We go over the best available evidence for the oral antihistamines and try to figure out which one is the “best”. In addition, we look at the evidence for intranasal corticosteroids and they are likely more effective than oral antihistamines.

Show Notes

Tools For Practice

Antihistamines for allergic rhinosinusitis: ‘Achoo’sing the right treatment

Episode 513: To Pee or Not to Pee: Combination agents for benign prostatic hypertrophy

In episode 513, James and Mike invite Emelie Braschi to the podcast for the first time. We go over the best available evidence around the treatment of BPH and focus on the combination therapy of alpha-blockers and 5-alpha reductase and find as for many things there is an improvement in symptoms but also an increase in side effects.

Show Notes

Tools For Practice

To Pee or Not to Pee: Combination agents for benign prostatic hypertrophy

Episode 512: Alcohol, the cause of, and solution to, all of life’s problems – PART II

In episode 512, James and Mike finish going over the best available evidence around drinking alcohol. We look at what evidence says about the “red-wine” theory and the French Paradox. We also look at the evidence around alcohol and surrogate markers, and atrial fibrillation. We also examine the effect of social drinking on emotion and alcohol-induced cirrhosis.

Show Notes

Check out the book “The Nutrition Proposition” for all the references discussed. The book is available on Amazon as a paperback and a Kindle Edition

Website

Amazon link

Episode 511: Alcohol, the cause of, and solution to, all of life’s problems

In episode 511, James and Mike go on a binge and dissect the best available evidence around alcohol – more specifically 0-3 drinks a day. We look at what is a “drink” and then dive into one of the largest reviews of alcohol ever done. We explore what that evidence suggests about the harms and the benefits, and as always we discuss what the numbers really say.

Show Notes

Check out the book “The Nutrition Proposition” for all the references discussed. The book is available on Amazon as a paperback and a Kindle Edition

  1. Website
    nutritionproposition.com
  2. Amazon link

Episode 509: Removing the pain from dealing with chronic pain – PART IV

In episode 509, James, Mike and Tina finish talking about our new clinical practice guideline on chronic pain. We focus on the top questions we all have in chronic pain and also discuss the best available evidence for the many different medications we use for chronic pain.

Show Notes

  1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
  2. Guideline summary
  3. Patient Handout
  4. PEER pain calculator
  5. Tame the Beast

 

Episode 508: Removing the pain from dealing with chronic pain – PART III

In episode 508, James and Mike ask Tina to come in and talk about our new clinical practice guideline on chronic pain. We focus on the best available evidence which shows that physical activity is key (except for neuropathic pain). We also go over the role for psychological interventions and the problem with opioids.

Show Notes

  1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
  2. Guideline summary
  3. Patient Handout
  4. PEER pain calculator

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The 2025 MEME Conference – May 9-10, 2025

REGISTRATION COMING SOON

Making Evidence Matter For Everyone | May 9-10, 2025
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice

hectalks.com

BIG ANNOUNCEMENT

THE NUTRITION PROPOSITION BOOK

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

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