In episode 503, James and Mike explore the evidence around water for a variety of different health outcomes. How much do we need and does it matter where we get it from? The only thing we know is that 8 glasses a day is wrong.
Show Notes
Coming soon
In episode 502, James, Mike Kolber and Tony Nickonchuk get together to talk about the easy question (just kidding) of COVID vaccines for children and adolescents. We discuss the best evidence we could find around efficacy and adverse effects in these age groups and hopefully give enough context so that you go from murky to somewhat less cloudy as to what we know and don’t know about this topic.
Show Notes
1) Tools for Practice
CO-KID: Covid vaccine for kids
2) Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents
January 12, 2022 DOI: 10.1056/NEJMoa2117995
James and Mike celebrate their 500th, YIKES, podcast episode. You get to hear the entire intro song (Some People) written and recorded by Pete McCormack. We talk about the history of the podcast, thank a lot of people, and talk about the key messages and the philosophy we have tried to impart over the years. We then discuss a few cases that bring all these ideas into focus. THANKS SO MUCH FOR LISTENING and going on this journey with us. We have had a blast.
Show Notes
In episode 499, James and Mike invite Tina back again to discuss the evidence we have for dieting to lose weight and the impact of that on osteoarthritis knee pain. Overall, there isn’t a lot of evidence but some observational data suggests a benefit Unfortunately the relatively small weight loss achieved from most diets in RCTs did not demonstrate a difference on OA pain.
Show Notes
Tools for Practice
No Gain, No Pain? – What is the effect of diet-induced weight loss on osteoarthritis-related knee pain?
In episode 498, James and Mike invite Tina back yet again to talk about all the evidence we have for using compression stockings in patients with chronic lower limb edema. The NNT for recurrent cellulitis is pretty good (listen to find out the actual number) on the “NNT scale”.
Show Notes
Tools for Practice
Under Pressure: Compression stockings for recurrent cellulitis?
In episode 497, James and Mike decide to go all in on the evidence around nutrition. We start out by going over how we try to actually figure out if a food is beneficial or harmful for you. And for nutrition is it ever tricky.
Show Notes
The Nutrition Proposition – Coming Soon – I hope
In episode 496, Mike and James continue the discussion with Ricky around the best available evidence we have for heart failure patients with preserved ejection fraction. Unfortunately, not much works but at least you’ll know the evidence.
Show Notes
In episode 495, Mike and James invite Ricky back again to talk about the options (not a lot) we have for heart failure patients with preserved ejection fraction. Ricky goes over all the trials and helps put them into context.
Show Notes
In episode 494, Mike and James invite Ricky Turgeon to talk about a potential new use for an old drug – colchicine. Ricky explains all the evidence we have for low-dose colchicine in people with a history of cardiovascular disease. We find out that colchicine reduces the risk of a cardiovascular event in a similar magnitude to statins – but will they be used as much as statins.? Find out what we think.
Show Notes
Tools for Practice
Cardiovascular prevention trials: Now calling colchicine to the stand
In episode 493, Mike and James review all the Long COVID data. We talk about how many people get it, what the symptoms are and how long it can persist – and it can be a long time. COVID long-term is different than what we see with the regular flu.
Show Notes
Tools for Practice
Long COVID: A (somewhat) short summary of risks, symptoms, and natural course
THE NUTRITION PROPOSITION BOOK
Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.
This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)
