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Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 133: Antipsychotics – schizophrenia the drugs – part 2

In episode 133, Mike and James again welcome Adil Virani to help us along with our antipsychotic drug discussion. We discuss the differences between the first and second generation antipsychotics, how to start, and when to consider a depot preparation. At the end of the podcast James realises that he has basically been hearing voices for the entire podcast but was reassured to find out the voices were actually Mike and Adil’s and that in general, they were telling the truth. 

Show notes

1) CATIE

N Engl J Med 2005;353:1209–23

2) CUtLASS 1

Arch Gen Psychiatry 2006;63:1079–87

Schizophr Bull 2006;32:715–23

3) Haloperiodol vs risperidone

N Engl J Med 2002;346:16-22

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